Peptidases • Haptophyta
Annotations/GenomesChrsp_1Emihu1Pavlov2436_1Phaant1Phaglo1TotalAnnotation Description
Merops
2556223164553572,005
1383232168Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2244416Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3156354935206Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1533214Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1334112Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
22Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11327Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
36412833Families of peptidase inhibitors not assigned to clans
1113
123
11
11
11
128920
1223210
2215
11114Families of metallopeptidases not assigned to clans
82917191891Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
78311534Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
4786934Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
3422314Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
6111010845Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
4969533Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
41565434Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
213Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4455523Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
23229Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
8306101266Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2250242923148Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
515107542Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
7613Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
221229Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
321114443Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
64213102150103632Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
414210636Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
31047731Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
102111151774Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
1938425Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1135Families of peptidases of unknown catalytic mechanism not assigned to clans
3144203021146
11
11