Peptidases • Chlorophyta
Annotations/GenomesAstpho2Auxeprot1Batpra1ChlNC64A_1Chlre4Chrzof1Coc_C169_1Dicre1Dunsal1Gonpec1MicpuC3v2MicpuN3v2Monneg1Ost9901_3OstRCC809_2Ostta1115_2Ostta4221_3Picsp_1Rapsub1SceoblEN4_1Sobl393_1SymretAf1SymretSc1SymretSp1SymretSw1Volca1TotalAnnotation Description
Merops
2721931553092873152713062802771761983582291021731661662572983662982943052813256,657
422239711121254222429991194118Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
3323323422334533323234443379Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
111121119Water nucleophile; water bound by two Asp
2517162529212024192019193230101519151420272523292526564Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
313351654113111132456767484Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
31113412251111213233445Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111111111112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11111121111113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2222211322332223312112222252Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
54464565453423333453455556111Families of peptidase inhibitors not assigned to clans
112
2114
2114111245123
11111112111113
11114
1113
111111111111113
11
162111171122
1221231233222228
11
111115
332251324312131211121122251Families of metallopeptidases not assigned to clans
1184244425111514449828848591525331415141588498Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
5223464343449222224742332290Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
311142674111121111143433167Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
13122411322252222231111147Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
66675988865699465689788888183Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1356810111012101256135385379121213121112233Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
6589696116949562446557111112118185Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
5323344233223332222311111263Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
112111213215Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
83443364735455354344445443111Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111312111121112221111131Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
4232571258487719724612119799978211Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
281816251825212118192022272291619182522292521242119548Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1185891110612756953454961476767190Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
42211786637Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111111118Serine or threonine nucleophile; N-terminal nucleophile
841133967733111111126253966665181Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7461447674958289746850571006427504541859110385848480641,847Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
121133111222121Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
45143366412423332355657653101Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111111110Serine nucleophile; catalytic residues in the order His, Ser, His in sequence
11122112311312211111231Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
171010121012161910118912117131010101316181519168322Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111111118Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
15118Serine nucleophile; catalytic residues in the order Lys, Ser in sequence
85658778676947256663488777162Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1449Families of peptidases of unknown catalytic mechanism not assigned to clans
43313147872410231293564151646311174
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