Peptidases • Ochrophyta
Annotations/GenomesAuran1Ectsil1Fracy1Nangad1Nanoce1779_2Ochro2298_1Pelago2097_1Phatr2Psemu1Thaoce1Thaps3TotalAnnotation Description
Merops
3842333702282574043582433272662923,362
66794547710570Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1214Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
3454443431338Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1113Water nucleophile; water bound by two Asp
11Water nucleophile; water bound by Asp and His; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
6423431828464026402829385Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
327442262537Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
33421174133142Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1131118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
9123433141334Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
7695588778979Families of peptidase inhibitors not assigned to clans
1113
325
112
111115
112
11
11
816217
22217
11
213
11112131112Families of metallopeptidases not assigned to clans
2210271212281018171722195Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
237134222Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
66169107233356Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
8353244433241Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
101195998676787Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
10699891471051097Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11445676442356Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2321523321Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
5553544453649Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
11Water nucleophile; water bound by a metal ion but ligands unknown.
121217Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
623313566302128141Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3329333030473429303929363Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5486588457464Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
2125Serine or threonine nucleophile; N-terminal nucleophile
618461541054669Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8764926365848760825968811Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
44765412639Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3553385362548Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11121122112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1291499111112161410127Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
9871599111041083Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112
351310813256088512197
11