Peptidases • Apicomplexa
Annotations/GenomesPlafal1Toxgon1TotalAnnotation Description
Merops
8774161
10515Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
8513Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
448Families of peptidase inhibitors not assigned to clans
11
22
11
112
448Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
549Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
123Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
112Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
123Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
151631Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
325Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
112Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
161127Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
224Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
5510Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
33