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Peptidases • Labyrinthulomycota
Annotations/GenomesAplke1Aurli1Schag1TotalAnnotation Description
Merops
3463393821,067
35210Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
53311Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
395452145Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
35715Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
2114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
55919Families of peptidase inhibitors not assigned to clans
11
11
11
1528
112Families of metallopeptidases not assigned to clans
23232268Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
85316Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2338Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1225Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
77721Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13111135Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
75618Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
65617Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
17212563Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
25232270Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
44412Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2114Serine or threonine nucleophile; N-terminal nucleophile
384051Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1188786291Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
711523Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3249Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
3339Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
44412Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22Families of peptidases of unknown catalytic mechanism not assigned to clans
262947102
112