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Peptidases • Ciliophora
Annotations/GenomesOxytri1Partet1Tetthe1TotalAnnotation Description
Merops
3326774701,479
11Families of aspartic peptidases not assigned to clans
274147115Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
28212Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
73164134371Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
43613Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1214Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1236Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
123Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
31114Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
1127745Families of peptidase inhibitors not assigned to clans
1010
22
1214
11
151117
44
224Families of metallopeptidases not assigned to clans
8193360Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
113115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to His, Asp and His
538Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2428Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1013730Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1181029Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
224Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
69520Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
22Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
2215Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
19452892Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
22111346Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
88172108368Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
423835Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
2327Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
39719Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
615829Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
747862
134