Peptidases • Rhizaria
Annotations/GenomesBigna1Retfil1TotalAnnotation Description
Merops
4051,0531,458
181331Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
538Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
6273135Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
22830Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
268Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
314Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
6511Families of peptidase inhibitors not assigned to clans
11
1515
11
11
112
33
22
11
11
112Families of metallopeptidases not assigned to clans
174259Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
729Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
61218Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
213Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
11718Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
102030Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
7512Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
44Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
358Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
7815Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
272956Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
141226Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
44Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11Serine or threonine nucleophile; N-terminal nucleophile
7613Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
111105216Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
9615Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
6511Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order His, Ser, His in sequence
224Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
527Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
628Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
224Families of peptidases of unknown catalytic mechanism not assigned to clans
11
32620652
11
112