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PFAM Domains • Excavata
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Annotations/GenomesGiaint1Naegr1Trivag1Trybru1TotalAnnotation Description
PFAMs
3,5728,83732,6476,13751,193
26444349162ATPase family associated with various cellular activities (AAA)
22819622221ABC transporter
233513ATP synthase alpha/beta family, nucleotide-binding domain
26365EGF-like domain
828122169Elongation factor Tu GTP binding domain
93113Hsp20/alpha crystallin family
6229913140Hsp70 protein
2113218KH domain
33SH2 domain
16925SH3 domain
4863211133Actin
15312093431,210Ankyrin repeat
733371693ADP-ribosylation factor family
314Eukaryotic aspartyl protease
2913933Cyclic nucleotide-binding domain
33Cystatin domain
112Cytochrome c
325Double-stranded RNA binding motif
19461102EF hand
122164Fe-4S binding domain
11Intermediate filament protein
112Fibronectin type III domain
1171221Glutathione S-transferase, C-terminal domain
216413Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
516Homeodomain
22Kazal-type serine protease inhibitor domain
11415Laminin EGF domain
1316424lactate/malate dehydrogenase, NAD binding domain
33Ligand-gated ion channel
22Lipocalin / cytosolic fatty-acid binding protein family
11213Myosin head (motor domain)
52254Cytochrome P450
2554029551691,781Protein kinase domain
31413737Pyridine nucleotide-disulphide oxidoreductase
1415236424554Ras family
32941Response regulator receiver domain
1131116RNase H
85313055246RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
71210Reverse transcriptase (RNA-dependent DNA polymerase)
11112Serpin (serine protease inhibitor)
11Copper/zinc superoxide dismutase (SODC)
47415Iron/manganese superoxide dismutases, alpha-hairpin domain
11750270Subtilase family
2851566Sugar (and other) transporter
11198514129Thioredoxin
11Snake toxin and toxin-like protein
1515Trypsin
830251275Tubulin/FtsZ family, GTPase domain
24327von Willebrand factor type A domain
1164122Zinc finger, C2H2 type
2442250Zinc finger, C3HC4 type (RING finger)
51713Zinc knuckle
13116Protein-tyrosine phosphatase
456111182short chain dehydrogenase
323338Zinc-binding dehydrogenase
1427Thiolase, N-terminal domain
325Beta-ketoacyl synthase, N-terminal domain
1592172Fe-2S iron-sulfur cluster binding domain
27364912124Papain family cysteine protease
129113Enolase, C-terminal TIM barrel domain
241411Glutamine amidotransferase class-I
916191357TCP-1/cpn60 chaperonin family
2215Glutamine synthetase, catalytic domain
11215Triosephosphate isomerase
1118321475E1-E2 ATPase
11157548149Core histone H2A/H2B/H3/H4
122023Alpha amylase, catalytic domain
11Metallothionein
186520Bacterial transferase hexapeptide (six repeats)
398323tRNA synthetases class I (I, L, M and V)
71228653Cyclin, N-terminal domain
628Carboxylesterase family
349420DNA polymerase family B
345719ATP synthase subunit C
22Peroxidase
66113Beta-lactamase
213C-5 cytosine-specific DNA methylase
174717328265Calcineurin-like phosphoesterase
213Cellulase (glycosyl hydrolase family 5)
374519tRNA synthetases class II (D, K and N)
4662779Mitochondrial carrier protein
11recA bacterial DNA recombination protein
51222847Aminotransferase class I and II
271616Phosphoribosyl transferase domain
219132458Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
11248Phosphoglycerate kinase
118212Ribosomal protein S4/S9 N-terminal domain
118212Ribosomal protein S12/S23
426Chaperonin 10 Kd subunit
11Fibroblast growth factor
765211139C2 domain
3954699PH domain
123bZIP transcription factor
1111518Aldehyde dehydrogenase family
7676Fungal Zn(2)-Cys(6) binuclear cluster domain
5176937Cytochrome b5-like Heme/Steroid binding domain
11Oxidoreductase molybdopterin binding domain
11121630Oxidoreductase NAD-binding domain
626271473SNF2 family N-terminal domain
11619Ribosomal protein S7p/S5e
12324415103Ubiquitin-conjugating enzyme
4127Isocitrate/isopropylmalate dehydrogenase
11529Ribosomal Proteins L2, RNA binding domain
44Chitinase class I
357318Hsp90 protein
11417Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
112Dihydrofolate reductase
347Cysteine-rich secretory protein family
116210Ribosomal protein S3, C-terminal domain
1111Annexin
112Eukaryotic-type carbonic anhydrase
11Chalcone and stilbene synthases, N-terminal domain
5382-oxoacid dehydrogenases acyltransferase (catalytic domain)
22Catalase
617Aminotransferase class-III
11428Ribosomal protein S19
12126DNA gyrase B
213Lyase
135110Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
33Sodium:neurotransmitter symporter family
112Ferritin-like domain
210911057278Adenylate and Guanylate cyclase catalytic domain
11ATP synthase delta (OSCP) subunit
112Orotidine 5'-phosphate decarboxylase / HUMPS family
11Bacterial DNA-binding protein
33ATP:guanido phosphotransferase, C-terminal catalytic domain
11Aromatic amino acid lyase
22217Pyruvate kinase, barrel domain
26421948135Kinesin motor domain
9254164139DnaJ domain
1414161559Proteasome subunit
235Major intrinsic protein
11ATP synthase
123Glycosyl hydrolase family 1
17456593'5'-cyclic nucleotide phosphodiesterase
221124Profilin
124310Ribosomal protein L22p/L17e
116311Ribosomal protein L14p/L23e
5439610154Ubiquitin family
1210224Cofilin/tropomyosin-type actin-binding protein
152533414-3-3 protein
11Alkaline phosphatase
6711327Zinc carboxypeptidase
21723345Aldo/keto reductase family
3401771221Myb-like DNA-binding domain
11Forkhead domain
11Glycosyl hydrolases family 32 N-terminal domain
1539Ribosomal protein L16p/L10e
167Ribosomal protein S14p/S29e
6109631FKBP-type peptidyl-prolyl cis-trans isomerase
71412Glutathione peroxidase
33
2106523Flavodoxin
11Tropomyosin
219223Calreticulin family
11316Thymidine kinase
3216324Aminotransferase class-V
347Ribonucleotide reductase, small chain
34577554220DEAD/DEAH box helicase
44789869289Helicase conserved C-terminal domain
112Fructose-bisphosphate aldolase class-I
125311Ribosomal protein L23
156113Pyridoxal-dependent decarboxylase, C-terminal sheet domain
116210Ribosomal protein L5
5128Pyridoxal-dependent decarboxylase conserved domain
314Citrate synthase, C-terminal domain
218516GHMP kinases N terminal domain
538Biotin carboxylase, N-terminal domain
1714224Pyridoxal-phosphate dependent enzyme
11'Paired box' domain
42114645NUDIX domain
124310pfkB family carbohydrate kinase
126312Ribosomal protein L3
137415Ribosomal protein L11, RNA binding domain
2571024Histidine phosphatase superfamily (branch 1)
1113Thymidylate synthase
233311ATP synthase alpha/beta chain, C terminal domain
11813234Calponin homology (CH) domain
1315Glutamine amidotransferases class-II
127212Ribosomal protein S15
44'Cold-shock' DNA-binding domain
22Fructose-1-6-bisphosphatase, N-terminal domain
1113Ribonucleotide reductase, all-alpha domain
11529Ribosomal protein S2
22SRF-type transcription factor (DNA-binding and dimerisation domain)
55GATA zinc finger
11718Amino acid permease
251513Prolyl oligopeptidase family
11338Ribosomal protein L30p/L7e
3728341Histidine phosphatase superfamily (branch 2)
516Aconitase family (aconitate hydratase)
125210Ribosomal protein S5, N-terminal domain
246416Nucleoside diphosphate kinase
28230Tetraspanin family
1157Ribosomal protein S10p/S20e
213Arrestin (or S-antigen), N-terminal domain
11316Phosphoglucose isomerase
123Carbohydrate phosphorylase
11518SecY translocase
11125Ribosomal protein L6
13329Polyprenyl synthetase
22Hexokinase
149519Dynamin family
33Biopterin-dependent aromatic amino acid hydroxylase
11215Transcription factor TFIID (or TATA-binding protein, TBP)
718Rieske [2Fe-2S] domain
12618Biotin-requiring enzyme
1111114Phosphofructokinase
126312Ribosomal protein S17
12317Hydroxymethylglutaryl-coenzyme A reductase
144514FGGY family of carbohydrate kinases, N-terminal domain
235FERM central domain
11Sodium:dicarboxylate symporter family
13821Enoyl-CoA hydratase/isomerase
127313Ribosomal protein S9/S16
1214Transcription factor TFIIB repeat
343313Cytidine and deoxycytidylate deaminase zinc-binding region
64450Chromo (CHRromatin Organisation MOdifier) domain
314Phosphatidylinositol-specific phospholipase C, Y domain
3227Phosphatidylinositol-specific phospholipase C, X domain
369D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
1412219Malic enzyme, N-terminal domain
1210114PEP-utilising enzyme, mobile domain
11Bacterial regulatory proteins, gntR family
113166-phosphogluconate dehydrogenase, C-terminal domain
11S-layer homology domain
198826WW domain
12126Ribosomal RNA adenine dimethylase
57185246109597WD domain, G-beta repeat
314Heavy-metal-associated domain
3912731Adenylate kinase
226111Phosphoglucomutase/phosphomannomutase, C-terminal domain
11338Ribosomal protein S8
11518Ribosomal protein S11
112114LIM domain
179834Regulator of chromosome condensation (RCC1) repeat
119213Ribosomal protein S13/S18
11Phycobilisome Linker polypeptide
331883260s Acidic ribosomal protein
112CUB domain
257216Prenyltransferase and squalene oxidase repeat
31114Protein kinase C terminal domain
11Spectrin repeat
112Single-strand binding protein family
127919S-adenosylmethionine synthetase, N-terminal domain
461175132Bromodomain
14115Acyl-CoA dehydrogenase, C-terminal domain
62114115183Ubiquitin carboxyl-terminal hydrolase
33Ribonuclease T2 family
254213SRP54-type protein, GTPase domain
10313Serine carboxypeptidase
11Ribosomal protein L20
515541084Phosphatidylinositol 3- and 4-kinase
12216Transketolase, thiamine diphosphate binding domain
127313Inositol monophosphatase family
1269Glutaredoxin
213Serine hydroxymethyltransferase
512329Iron-containing alcohol dehydrogenase
249318Ribosomal protein L10
1811828KOW motif
246RF-1 domain
11Sodium:solute symporter family
2158DNA polymerase family A
123IMP dehydrogenase / GMP reductase domain
11316Glucose-6-phosphate dehydrogenase, NAD binding domain
134ROK family
69191044Protein phosphatase 2C
154212Nucleotidyl transferase
325Carbonic anhydrase
22812Phosphoribulokinase / Uridine kinase family
17421Fatty acid desaturase
254516MutS domain V
3317Arginase family
697830MCM P-loop domain
123Squalene/phytoene synthase
28131134FHA domain
726181061AMP-binding enzyme
39847G-protein alpha subunit
31639159HMG (high mobility group) box
29736His Kinase A (phospho-acceptor) domain
1205329Armadillo/beta-catenin-like repeat
121102816166Tetratricopeptide repeat
10212Ion transport protein
12126DNA gyrase/topoisomerase IV, subunit A
22011235BRCA1 C Terminus (BRCT) domain
153312Glycosyl transferases group 1
135110Glycosyl transferase family 2
2124321SAM domain (Sterile alpha motif)
11linker histone H1 and H5 family
22Ribosomal protein L7/L12 C-terminal domain
11Pectate lyase
36211CoA-ligase
617Phosphopantetheine attachment site
112Formyl transferase
3913631Metallopeptidase family M24
73872816438Leucine Rich Repeat
9110alpha/beta hydrolase fold
333312RNA polymerase Rpb2, domain 6
13114PB1 domain
135211Staphylococcal nuclease homologue
312691397Rab-GTPase-TBC domain
1517Tudor domain
224WH1 domain
15217Zinc finger, ZZ type
1528HRDC domain
511622CBS domain
127313Ribosomal protein L13
12429Ribosomal protein L4/L1 family
11417S1 RNA binding domain
538319AhpC/TSA family
242311tRNA synthetases class I (W and Y)
2215UvrD/REP helicase N-terminal domain
4720839Rhodanese-like domain
737261181Acetyltransferase (GNAT) family
314SecE/Sec61-gamma subunits of protein translocation complex
112AIR synthase related protein, N-terminal domain
4115424tRNA synthetase class II core domain (G, H, P, S and T)
1348SpoU rRNA Methylase family
819Phage integrase family
1124Tetrapyrrole (Corrin/Porphyrin) Methylases
22Class II Aldolase and Adducin N-terminal domain
617Diacylglycerol kinase accessory domain
33Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
236171166IQ calmodulin-binding motif
11111225Phosphoinositide 3-kinase family, accessory domain (PIK domain)
415Phospholipase D Active site motif
29736Regulator of G protein signaling domain
101323GTPase-activator protein for Ras-like GTPase
271946RasGEF domain
10515RasGEF N-terminal motif
32526155RhoGAP domain
2421146RhoGEF domain
152926SPRY domain
344415RNA polymerase Rpb1, domain 2
12429Guanylate kinase
65213Gelsolin repeat
1231750UBA/TS-N domain
613120PHD-finger
55Filamin/ABP280 repeat
48651188HECT-domain (ubiquitin-transferase)
314Helix-hairpin-helix motif
1214MSP (Major sperm protein) domain
1315Ribonuclease III domain
1113520Region in Clathrin and VPS
129113RanBP1 domain
2338PPIC-type PPIASE domain
178Zn-finger in Ran binding protein and others
21561437Zinc finger C-x8-C-x5-C-x3-H type (and similar)
11218233B-box zinc finger
29112Poly(ADP-ribose) polymerase catalytic domain
224Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
33913343F-box domain
1124Elongation factor 1 gamma, conserved domain
18101543Calpain family cysteine protease
9514CRAL/TRIO domain
6035196BTB/POZ domain
77Ricin-type beta-trefoil lectin domain
11Inhibitor of Apoptosis domain
73313Voltage gated chloride channel
15520Caspase domain
44GDSL-like Lipase/Acylhydrolase
123Poly-adenylate binding protein, unique domain
127111POLO box duplicated region
73334579ABC transporter transmembrane region
2525Integrase core domain
262414FAD binding domain
11Condensation domain
1315S-adenosyl-L-homocysteine hydrolase, NAD binding domain
3434HAMP domain
116210ribosomal L5P family C-terminus
2107625Insulinase (Peptidase family M16)
448Dehydrogenase E1 component
1144827Elongation factor G C-terminus
1315HMGL-like
237820DnaJ central domain
11314Starch binding domain
218415Ribosomal protein L1p/L10e family
3910628Cation transporting ATPase, C-terminus
3711728Cation transporter/ATPase, N-terminus
213dUTPase
516Aconitase C-terminal domain
1236Amino acid kinase family
213Acyl transferase domain
11Dihydrodipicolinate synthetase family
327191059haloacid dehalogenase-like hydrolase
44Glycosyl hydrolases family 2
112Glycosyl hydrolases family 18
11215Proliferating cell nuclear antigen, N-terminal domain
11Translation initiation factor IF-3, C-terminal domain
1416Acylphosphatase
112Adenylosuccinate synthetase
213Asparaginase, N-terminal
325Peptidase S24-like
44311Inorganic pyrophosphatase
88Glycosyl hydrolases family 16
235Glycosyl hydrolases family 15
11218132NADH:flavin oxidoreductase / NADH oxidase family
21143-hydroxyacyl-CoA dehydrogenase, C-terminal domain
358Glycosyl hydrolase family 20, catalytic domain
124310HhH-GPD superfamily base excision DNA repair protein
224GMC oxidoreductase
11114Asparagine synthase
11136EF-1 guanine nucleotide exchange domain
213Flavin-binding monooxygenase-like
233210tRNA synthetases class I (E and Q), catalytic domain
12115tRNA synthetases class I (R)
246315XPG N-terminal domain
51019438Metallo-beta-lactamase superfamily
134448F5/8 type C domain
55Choline/Carnitine o-acyltransferase
22Putative esterase
11Ferrochelatase
213Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
11Arginosuccinate synthase
112Electron transfer flavoprotein FAD-binding domain
281314RNB domain
11Dioxygenase
112CNH domain
210416Diacylglycerol kinase catalytic domain
426111657Dual specificity phosphatase, catalytic domain
11112MyTH4 domain
13610P21-Rho-binding domain
5149432PX domain
213Ras association (RalGDS/AF-6) domain
64212UBX domain
1225VHS domain
148114Phosphoinositide 3-kinase C2
33PI3-kinase family, ras-binding domain
6118Carbon-nitrogen hydrolase
22N-acetyltransferase
628Syntaxin
1313Pentapeptide repeats (8 copies)
465621Pumilio-family RNA binding repeat
26210Histone-like transcription factor (CBF/NF-Y) and archaeal histone
11Pterin binding enzyme
11215ER lumen protein retaining receptor
12115Glycoprotease family
2221117impB/mucB/samB family
189Phosphoenolpyruvate carboxykinase C-terminal P-loop domain
11
11428Ribosomal L15
2112419Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
112Ribosomal prokaryotic L21 protein
11Ribosomal L28 family
11428Ribosomal L29 protein
516Ribosomal L39 protein
117211Ribosomal S17
11114Ribulose-phosphate 3 epimerase family
11226Translationally controlled tumour protein
11Alanine racemase, C-terminal domain
2112722RNA pseudouridylate synthase
159419Histone deacetylase domain
22POT family
112PWWP domain
5882950SET domain
12126Isochorismatase family
11Permease family
11529Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
246315XPG I-region
11Transposase, Mutator family
123DNA photolyase
2911NlpC/P60 family
11Cation-independent mannose-6-phosphate receptor repeat
3116323Nitroreductase family
33Zinc dependent phospholipase C
235Cytosol aminopeptidase family, catalytic domain
22830Sulfatase
11Ribosomal protein S16
347Acyl CoA binding protein
712726Cullin family
112Elongation factor TS
347FAD binding domain
4615126EamA-like transporter family
22
51514943ThiF family
116210Ribosomal family S4e
66Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
11Penicillin binding protein transpeptidase domain
33dTDP-4-dehydrorhamnose 3,5-epimerase
639Ammonium Transporter Family
11Transglycosylase
4343Trypanosome variant surface glycoprotein (A-type)
11Sulfate permease family
224MATH domain
1113Uncharacterized protein family UPF0004
1214Transaldolase/Fructose-6-phosphate aldolase
11Mechanosensitive ion channel
2414424Adaptor complexes medium subunit family
1103822Exonuclease
112Dipeptidyl peptidase IV (DPP IV) N-terminal region
44Glycosyl hydrolase family 3 N terminal domain
128213Ribosomal protein L44
210113Sodium:sulfate symporter transmembrane region
112DNA-dependent RNA polymerase
336FAD binding domain in molybdopterin dehydrogenase
11114Glycosyl transferase family 4
112HCO3- transporter family
246Nucleosome assembly protein (NAP)
31012631Synaptobrevin
112GMP synthase C terminal domain
42410Adenosine/AMP deaminase
14914Oxidoreductase FAD-binding domain
11Glycosyltransferase family 20
235UDP-glucose/GDP-mannose dehydrogenase family, central domain
112Carbamoyl-phosphate synthase small chain, CPSase domain
348143PAS fold
4821437Sec1 family
13228GDP dissociation inhibitor
123Sodium/hydrogen exchanger family
22228RNA polymerase Rpb3/RpoA insert domain
343414Initiation factor 2 subunit family
11PQQ enzyme repeat
123Electron transfer flavoprotein domain
164213Ribosomal S3Ae family
11Ribosomal L27 protein
314GTP1/OBG
33Gamma-glutamyltranspeptidase
156Ribosomal L40e family
11215GrpE
333413TatD related DNase
112Inhibitor of apoptosis-promoting Bax1
112Eukaryotic DNA topoisomerase I, catalytic core
128213Dynamin central region
22Syndecan domain
116-O-methylguanine DNA methyltransferase, DNA binding domain
1326Carboxyl transferase domain
224UbiA prenyltransferase family
55DegT/DnrJ/EryC1/StrS aminotransferase family
2439Endoribonuclease L-PSP
4110217Phosphorylase superfamily
4217Cys/Met metabolism PLP-dependent enzyme
617225Glycosyl hydrolases family 31
314NADH ubiquinone oxidoreductase, 20 Kd subunit
145ABC-2 type transporter
21238Amino-transferase class IV
378422CDP-alcohol phosphatidyltransferase
279Calpain large subunit, domain III
151310ATP dependent DNA ligase domain
11FMN-dependent dehydrogenase
14273-beta hydroxysteroid dehydrogenase/isomerase family
5319Glycosyl hydrolases family 38 N-terminal domain
314Presenilin
11Ribosomal protein S18
314Clathrin light chain
2226Ubiquitin carboxyl-terminal hydrolase, family 1
11
1719Ribosomal protein S19e
136212Ribosomal protein S6e
11Receptor family ligand binding region
343414Transcription factor S-II (TFIIS)
22Glycophorin A
112Surface antigen
44917emp24/gp25L/p24 family/GOLD
538NifU-like domain
12216Cyclin-dependent kinase regulatory subunit
112Asparaginase
156F-actin capping protein, beta subunit
189Fructose-bisphosphate aldolase class-II
1427DNA mismatch repair protein, C-terminal domain
22Alpha-L-fucosidase
11114Dephospho-CoA kinase
55MAPEG family
112G10 protein
21339DNA topoisomerase
11Elongation factor P (EF-P) OB domain
11Glucose inhibited division protein A
112Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
1214RNA 3'-terminal phosphate cyclase
3656203' exoribonuclease family, domain 1
127111tRNA-splicing ligase RtcB
112610tRNA pseudouridine synthase D (TruD)
112Coenzyme A transferase
437SPFH domain / Band 7 family
14319Cytidylyltransferase family
10212GDA1/CD39 (nucleoside phosphatase) family
6410GNS1/SUR4 family
11215Hydroxymethylglutaryl-coenzyme A synthase N terminal
165214Inosine-uridine preferring nucleoside hydrolase
116210Ribosomal protein L21e
116210Ribosomal protein L36e
1214Ribosomal protein L6e
112Phosphatidylethanolamine-binding protein
11
332311RIO1 family
11213Tub family
12115Alanine racemase, N-terminal domain
11114Putative RNA methylase family UPF0020
534113PP-loop family
22419Shwachman-Bodian-Diamond syndrome (SBDS) protein
11Urocanase Rossmann-like domain
11114Translation initiation factor 1A / IF-1
2619Dihydroorotate dehydrogenase
314210Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
145Glycosyl hydrolases family 25
123Macrophage migration inhibitory factor (MIF)
26482016S rRNA methyltransferase RsmB/F
21227RNA polymerase Rpb5, C-terminal domain
11338RNA polymerase Rpb6
242210RNA polymerase Rpb3/Rpb11 dimerisation domain
11114RNA polymerases N / 8 kDa subunit
11Peptidyl-tRNA hydrolase
112Ribosomal protein L17
117211Ribosomal protein L31e
11428Ribosomal protein L34e
17210Ribosomal protein S28e
226313Ribosomal protein S8e
11Shikimate kinase
22Trehalase
1113Uncharacterized protein family UPF0029
347418Dihydrouridine synthase (Dus)
415ubiE/COQ5 methyltransferase family
17311NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
11
1315Beta-eliminating lyase
1113Adenylate cyclase associated (CAP) N terminal
2130134Casein kinase II regulatory subunit
3417630Clathrin adaptor complex small chain
228719Dynein light chain type 1
617Ergosterol biosynthesis ERG4/ERG24 family
224DNA/RNA non-specific endonuclease
6410Formate/nitrite transporter
11GTP cyclohydrolase I
11Glycosyl hydrolases family 39
12126HIT domain
11215Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
14510Oxysterol-binding protein
1113Phosphomannose isomerase type I
225312Protein prenyltransferase alpha subunit repeat
145Pyridoxamine 5'-phosphate oxidase
22Membrane dipeptidase (Peptidase family M19)
225312Ribosomal protein L24e
11417Ribosomal protein L35Ae
6522841Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
11226Ribosomal protein S21e
11Ribosomal protein S6
11428Ribosomal protein S7e
244313Translation initiation factor SUI1
21115Putative undecaprenyl diphosphate synthase
11114Carbohydrate kinase
1113Thioredoxin-like [2Fe-2S] ferredoxin
11Xylose isomerase-like TIM barrel
224Alanine dehydrogenase/PNT, C-terminal domain
1315Aldose 1-epimerase
1247FAD dependent oxidoreductase
134F-actin capping protein alpha subunit
11Formate--tetrahydrofolate ligase
11237Fibrillarin
11Transcription elongation factor, GreA/GreB, C-term
112LBP / BPI / CETP family, N-terminal domain
11428Ribosomal protein L19e
11Ribosomal protein L9, N-terminal domain
117211Ribosomal protein S24e
119112Ribosomal protein S26e
12216Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
213Phosphoenolpyruvate carboxykinase
116210Ribosomal protein L13e
11114Telomere recombination
224210CAP-Gly domain
11
336Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
11Creatinase/Prolidase N-terminal domain
11DSBA-like thioredoxin domain
129113Pyruvate phosphate dikinase, PEP/pyruvate binding domain
123Polypeptide deformylase
123Pterin 4 alpha carbinolamine dehydratase
1214mRNA capping enzyme, catalytic domain
498728OB-fold nucleic acid binding domain
11Peptidase family S49
1548265Kelch motif
11125Ribonuclease HII
224Poly A polymerase regulatory subunit
33Transposase (partial DDE domain)
88
1361323FYVE zinc finger
213RIH domain
2135'-3' exonuclease, C-terminal SAM fold
213DHH family
2416325Sec7 domain
2314625NAD dependent epimerase/dehydratase family
246Glycosyl hydrolase family 14
1315SIS domain
1113Helix-turn-helix
123Phosphate transporter family
213ARID/BRIGHT DNA binding domain
11314Collagen triple helix repeat (20 copies)
22Chromo shadow domain
11Clathrin propeller repeat
112Topoisomerase DNA binding C4 zinc finger
299626JAB1/Mov34/MPN/PAD-1 ubiquitin protease
21314837PCI domain
12115tRNA synthetases class I (C) catalytic domain
325Oxidoreductase family, NAD-binding Rossmann fold
12317tRNA synthetases class II core domain (F)
11125tRNA synthetases class II (A)
3821537Putative GTPase activating protein for Arf
11Delta serrate ligand
334414tRNA pseudouridine synthase
12216ENTH domain
224NF-X1 type zinc finger
1215191460LSM domain
246R3H domain
415Amidase
325BAH domain
224AN1-like Zinc finger
112Hsp33 protein
3126Peptidase family M3
64414Peptidase family M1 domain
31610Peptidase family M41
2417Peptidase family M48
1190191NHL repeat
11316Plexin repeat
118111Low molecular weight phosphotyrosine protein phosphatase
22MAGE family
3811094Leishmanolysin
235Eukaryotic porin
1326GRIP domain
12126Skp1 family, dimerisation domain
334414Cytidylyltransferase-like
112Pyroglutamyl peptidase
143210PUA domain
2439LysM domain
2715630S4 domain
123PWI domain
212629Proprotein convertase P-domain
710118IBR domain, a half RING-finger domain
1185342114Transmembrane amino acid transporter protein
1214Frataxin-like domain
22FAD binding domain
12519V-type ATPase 116kDa subunit family
44Transposase
1213117Glycosyl transferase family 8
272415Phosphatidylinositol-4-phosphate 5-Kinase
33Major Vault Protein repeat domain
1315Phosphoadenosine phosphosulfate reductase family
12115TruB family pseudouridylate synthase (N terminal domain)
1214Respiratory-chain NADH dehydrogenase 51 Kd subunit
1416ATP-NAD kinase
12418Iron-sulphur cluster biosynthesis
112Polysaccharide deacetylase
85491274DHHC palmitoyltransferase
11Glycosyl transferase family 11
429437Glycosyl hydrolase family 47
312639PPR repeat
134Adenosylmethionine decarboxylase
1113GIY-YIG catalytic domain
369CorA-like Mg2+ transporter protein
2914530Cation efflux family
289524Peptidase family M20/M25/M40
51010631Acyltransferase
3452564MatE
11DNA methylase
36211040DnaJ C terminal domain
33Fumarylacetoacetate (FAA) hydrolase family
279Pyruvate ferredoxin/flavodoxin oxidoreductase
213Spermine/spermidine synthase domain
12214FAD binding domain
3323332PAP2 superfamily
325Aminomethyltransferase folate-binding domain
213MaoC like domain
8210G-patch domain
125210Putative tRNA binding domain
232236GAF domain
1346-phosphofructo-2-kinase
11114NifU-like N terminal domain
66Flavin containing amine oxidoreductase
1225Cyclin M transmembrane N-terminal domain
44O-methyltransferase
1214Glycine cleavage H-protein
1010
11529Ribosomal protein S27a
51167891Adaptin N terminal region
13536Protein phosphatase 2A regulatory B subunit (B56 family)
22Transposase DDE domain
2525Transposase
2113163'-5' exonuclease
112Proline dehydrogenase
12227MutS domain I
11215Peptide methionine sulfoxide reductase
11Ribosomal protein L35
12126Choline/ethanolamine kinase
1113Phosphotransferase enzyme family
22ATPase domain predominantly from Archaea
11114SelR domain
11Methylmalonyl-CoA mutase
1310115Peptidase C13 family
3721637Eukaryotic initiation factor 4E
116210Ribosomal protein L32
11CobQ/CobB/MinD/ParA nucleotide binding domain
11619Myo-inositol-1-phosphate synthase
265114Macro domain
1416Type I phosphodiesterase / nucleotide pyrophosphatase
11417Ribosomal protein S27
11226Metalloenzyme superfamily
11Diaminopimelate epimerase
11215Riboflavin kinase
11Caulimovirus viroplasmin
7916Rhomboid family
639Sodium/calcium exchanger protein
235212Queuine tRNA-ribosyltransferase
235212UTP--glucose-1-phosphate uridylyltransferase
11Transcriptional regulator
2125Deoxynucleoside kinase
14128Smr domain
1214IPP transferase
112Cobalamin-independent synthase, Catalytic domain
325BolA-like protein
11114Ham1 family
455519FtsJ-like methyltransferase
11Quinolinate phosphoribosyl transferase, C-terminal domain
1391326Nucleoside transporter
88Patatin-like phospholipase
22Dienelactone hydrolase family
11619Poly A polymerase head domain
1113tRNA (Guanine-1)-methyltransferase