PFAM Domains • Cryptophyta
Annotations/GenomesCrypto2293_1Guith1TotalAnnotation Description
PFAMs
14,04913,73127,780
4462106ATPase family associated with various cellular activities (AAA)
8086166ABC transporter
549ATP synthase alpha/beta family, nucleotide-binding domain
11011EGF-like domain
202444Elongation factor Tu GTP binding domain
51318Helix-loop-helix DNA-binding domain
51318Hsp20/alpha crystallin family
352257Hsp70 protein
333265KH domain
33Methyl-accepting chemotaxis protein (MCP) signalling domain
11Ribulose bisphosphate carboxylase large chain, catalytic domain
51217SH3 domain
2020TNFR/NGFR cysteine-rich region
11u-PAR/Ly-6 domain
71219Actin
299463762Ankyrin repeat
11314PAN domain
121325ADP-ribosylation factor family
151833Eukaryotic aspartyl protease
3997136Cyclic nucleotide-binding domain
134Cytochrome c
5510Double-stranded RNA binding motif
6284290EF hand
444Fe-4S binding domain
224Fibronectin type II domain
72431Fibronectin type III domain
7714Globin
72128Glutathione S-transferase, C-terminal domain
257Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
55Homeodomain
134Kringle domain
628Laminin B (Domain IV)
7512Laminin EGF domain
336lactate/malate dehydrogenase, NAD binding domain
111324Lectin C-type domain
22Ligand-gated ion channel
101222Myosin head (motor domain)
66LNR domain
41418Cytochrome P450
310436746Protein kinase domain
92130Pyridine nucleotide-disulphide oxidoreductase
292352Ras family
131427Response regulator receiver domain
67122189RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
44Reverse transcriptase (RNA-dependent DNA polymerase)
617Serpin (serine protease inhibitor)
22Copper/zinc superoxide dismutase (SODC)
358Iron/manganese superoxide dismutases, alpha-hairpin domain
21113Subtilase family
8715Sugar (and other) transporter
3811Sushi repeat (SCR repeat)
5660116Thioredoxin
22Trefoil (P-type) domain
111122Trypsin
112Thrombospondin type 1 domain
10717Tubulin/FtsZ family, GTPase domain
235von Willebrand factor type A domain
11von Willebrand factor type D domain
631679Zinc finger, C2H2 type
10116126Zinc finger, C3HC4 type (RING finger)
41519Zinc knuckle
437Protein-tyrosine phosphatase
464288short chain dehydrogenase
92433Zinc-binding dehydrogenase
6410Thiolase, N-terminal domain
7613Beta-ketoacyl synthase, N-terminal domain
69152Fe-2S iron-sulfur cluster binding domain
91019Papain family cysteine protease
246Enolase, C-terminal TIM barrel domain
11Cytochrome C and Quinol oxidase polypeptide I
4711Glutamine amidotransferase class-I
121123TCP-1/cpn60 chaperonin family
8614Glutamine synthetase, catalytic domain
437Triosephosphate isomerase
242246E1-E2 ATPase
132134Core histone H2A/H2B/H3/H4
22Bacterial regulatory helix-turn-helix protein, lysR family
6511Alpha amylase, catalytic domain
101323Bacterial transferase hexapeptide (six repeats)
10818tRNA synthetases class I (I, L, M and V)
221335Cyclin, N-terminal domain
22Carboxylesterase family
9615DNA polymerase family B
347ATP synthase subunit C
246Legume lectin domain
11Sigma-70 factor, region 1.2
7613Peroxidase
336Beta-lactamase
224C-5 cytosine-specific DNA methylase
314Fibrinogen beta and gamma chains, C-terminal globular domain
314475Calcineurin-like phosphoesterase
257Cellulase (glycosyl hydrolase family 5)
101020tRNA synthetases class II (D, K and N)
6683149Mitochondrial carrier protein
142236Aminotransferase class I and II
41216Phosphoribosyl transferase domain
11Sigma-54 interaction domain
272855Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
448Phosphoglycerate kinase
213Ribosomal protein S4/S9 N-terminal domain
112Ribosomal protein S12/S23
224Chaperonin 10 Kd subunit
57134191C2 domain
138396PH domain
61117bZIP transcription factor
151530Aldehyde dehydrogenase family
39699Fungal Zn(2)-Cys(6) binuclear cluster domain
172138Cytochrome b5-like Heme/Steroid binding domain
213Oxidoreductase molybdopterin binding domain
81018Oxidoreductase NAD-binding domain
374582SNF2 family N-terminal domain
112Ribosomal protein S7p/S5e
343165Ubiquitin-conjugating enzyme
123Isocitrate/isopropylmalate dehydrogenase
224Ribosomal Proteins L2, RNA binding domain
5611Hsp90 protein
123Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
112Dihydrofolate reductase
11Cysteine-rich secretory protein family
213Ribosomal protein S3, C-terminal domain
51217Eukaryotic-type carbonic anhydrase
11Bacterial regulatory proteins, luxR family
3582-oxoacid dehydrogenases acyltransferase (catalytic domain)
7512Aminotransferase class-III
112Ribosomal protein S19
123DNA gyrase B
11Thiamine pyrophosphate enzyme, central domain
437Lyase
123Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
325Sodium:neurotransmitter symporter family
112Ferritin-like domain
7159130Adenylate and Guanylate cyclase catalytic domain
112ATP synthase delta (OSCP) subunit
112Orotidine 5'-phosphate decarboxylase / HUMPS family
7411ATP:guanido phosphotransferase, C-terminal catalytic domain
358Indole-3-glycerol phosphate synthase
9413Pyruvate kinase, barrel domain
7365138Kinesin motor domain
7387160DnaJ domain
181533Proteasome subunit
61117Major intrinsic protein
224ATP synthase
4616623'5'-cyclic nucleotide phosphodiesterase
224Profilin
314Ribosomal protein L22p/L17e
112Ribosomal protein L14p/L23e
393776Ubiquitin family
459Cofilin/tropomyosin-type actin-binding protein
33614-3-3 protein
235Alkaline phosphatase
61521Zinc carboxypeptidase
232346Aldo/keto reductase family
2190111Myb-like DNA-binding domain
22Ribosomal protein L16p/L10e
112Ribosomal protein S14p/S29e
324779FKBP-type peptidyl-prolyl cis-trans isomerase
7310Glutathione peroxidase
22
6814Flavodoxin
224Calreticulin family
112Thymidine kinase
141529Aminotransferase class-V
415Ribonucleotide reductase, small chain
5871129DEAD/DEAH box helicase
87123210Helicase conserved C-terminal domain
134Fructose-bisphosphate aldolase class-I
213EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
123Ribosomal protein L23
5510Pyridoxal-dependent decarboxylase, C-terminal sheet domain
112Ribosomal protein L5
134Pyridoxal-dependent decarboxylase conserved domain
123Citrate synthase, C-terminal domain
5813GHMP kinases N terminal domain
459Biotin carboxylase, N-terminal domain
112Tryptophan synthase alpha chain
71017Pyridoxal-phosphate dependent enzyme
242852NUDIX domain
4913pfkB family carbohydrate kinase
224Ribosomal protein L3
224Ribosomal protein L11, RNA binding domain
213556Histidine phosphatase superfamily (branch 1)
134Rubredoxin
112Thymidylate synthase
336ATP synthase alpha/beta chain, C terminal domain
7815Calponin homology (CH) domain
5712Glutamine amidotransferases class-II
224Phosphoenolpyruvate carboxylase
224Ribosomal protein S15
7512'Cold-shock' DNA-binding domain
5510Fructose-1-6-bisphosphatase, N-terminal domain
224Ribonucleotide reductase, all-alpha domain
213Ribosomal protein S2
358SRF-type transcription factor (DNA-binding and dimerisation domain)
44Amino acid permease
11718Prolyl oligopeptidase family
224Ribosomal protein L30p/L7e
448Histidine phosphatase superfamily (branch 2)
224Aconitase family (aconitate hydratase)
123Ribosomal protein S5, N-terminal domain
6713Nucleoside diphosphate kinase
112Tetraspanin family
213Ribosomal protein S10p/S20e
213Phosphoglucose isomerase
224Carbohydrate phosphorylase
112SecY translocase
112Ribosomal protein L6
5712Polyprenyl synthetase
112Hexokinase
18624Dynamin family
112Biopterin-dependent aromatic amino acid hydroxylase
161127Transcription factor TFIID (or TATA-binding protein, TBP)
33Pentaxin family
5914Rieske [2Fe-2S] domain
123Phytochrome region
7916Biotin-requiring enzyme
246Phosphofructokinase
123Ribosomal protein S17
11Hydroxymethylglutaryl-coenzyme A reductase
347FGGY family of carbohydrate kinases, N-terminal domain
112Sodium:dicarboxylate symporter family
8917Enoyl-CoA hydratase/isomerase
123Ribosomal protein S9/S16
4610Transcription factor TFIIB repeat
5712Cytidine and deoxycytidylate deaminase zinc-binding region
23932Chromo (CHRromatin Organisation MOdifier) domain
22Phosphatidylinositol-specific phospholipase C, Y domain
33Phosphatidylinositol-specific phospholipase C, X domain
6511D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
369Malic enzyme, N-terminal domain
112PEP-utilising enzyme, mobile domain
11Bacterial regulatory proteins, gntR family
11Multicopper oxidase
3780117WW domain
336Ribosomal RNA adenine dimethylase
347312659WD domain, G-beta repeat
437Heavy-metal-associated domain
11Dockerin type I domain
121426Adenylate kinase
325Phosphoglucomutase/phosphomannomutase, C-terminal domain
112Ribosomal protein S8
112Ribosomal protein S11
336LIM domain
6054114Regulator of chromosome condensation (RCC1) repeat
224Ribosomal protein S13/S18
336chorismate binding enzyme
461060s Acidic ribosomal protein
11617CUB domain
336Prenyltransferase and squalene oxidase repeat
22Protein kinase C terminal domain
112S-adenosylmethionine synthetase, N-terminal domain
192847Bromodomain
11Bacterial regulatory proteins, tetR family
5611Acyl-CoA dehydrogenase, C-terminal domain
363268Ubiquitin carboxyl-terminal hydrolase
112Ribosomal protein L36
11Ribonuclease T2 family
167HSF-type DNA-binding
347SRP54-type protein, GTPase domain
112Urease alpha-subunit, N-terminal domain
10414Serine carboxypeptidase
112Ribosomal protein L20
91726Phosphatidylinositol 3- and 4-kinase
235Transketolase, thiamine diphosphate binding domain
224WHEP-TRS domain
358Inositol monophosphatase family
71724Glutaredoxin
235Isocitrate lyase family
235Serine hydroxymethyltransferase
22Iron-containing alcohol dehydrogenase
325Ribosomal protein L10
22KOW motif
11Negative factor, (F-Protein) or Nef
112Ribosomal protein L33
358RF-1 domain
2810Sodium:solute symporter family
112Imidazoleglycerol-phosphate dehydratase
358DNA polymerase family A
224IMP dehydrogenase / GMP reductase domain
233962Protein phosphatase 2C
112Nucleotidyl transferase
459Carbonic anhydrase
246Phosphoribulokinase / Uridine kinase family
11Transcriptional regulatory protein, C terminal
121426Fatty acid desaturase
7815MutS domain V
213Delta-aminolevulinic acid dehydratase
112Arginase family
12820MCM P-loop domain
246Squalene/phytoene synthase
33Bacterial extracellular solute-binding proteins, family 3
223456FHA domain
292251AMP-binding enzyme
22Phycobilisome protein
402262Chlorophyll A-B binding protein
182139HMG (high mobility group) box
41418His Kinase A (phospho-acceptor) domain
315283Armadillo/beta-catenin-like repeat
45207252Tetratricopeptide repeat
46163209Ion transport protein
336DNA gyrase/topoisomerase IV, subunit A
11HlyD membrane-fusion protein of T1SS
231235Scavenger receptor cysteine-rich domain
61521BRCA1 C Terminus (BRCT) domain
92635Glycosyl transferases group 1
71825Glycosyl transferase family 2
132336SAM domain (Sterile alpha motif)
11linker histone H1 and H5 family
112Ribosomal protein L7/L12 C-terminal domain
11Urease, gamma subunit
123CoA-ligase
6511Phosphopantetheine attachment site
112Formyl transferase
11Cellulose binding domain
8917Metallopeptidase family M24
62237299Leucine Rich Repeat
33437alpha/beta hydrolase fold
235RNA polymerase Rpb2, domain 6
11EAL domain
5712PB1 domain
123Staphylococcal nuclease homologue
141832Rab-GTPase-TBC domain
123Tudor domain
358Zinc finger, ZZ type
33HRDC domain
41014CBS domain
134Ribosomal protein L13
224Ribosomal protein L4/L1 family
134Clp protease
6814S1 RNA binding domain
112HIUase/Transthyretin family
3811AhpC/TSA family
358tRNA synthetases class I (W and Y)
235UvrD/REP helicase N-terminal domain
41216Rhodanese-like domain
235Universal stress protein family
243963Acetyltransferase (GNAT) family
11SecE/Sec61-gamma subunits of protein translocation complex
11C-terminal regulatory domain of Threonine dehydratase
112AIR synthase related protein, N-terminal domain
131427tRNA synthetase class II core domain (G, H, P, S and T)
81321SpoU rRNA Methylase family
448Tetrapyrrole (Corrin/Porphyrin) Methylases
224Glycosyl transferase family, a/b domain
11TonB dependent receptor
11Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain
99199298PDZ domain
33Class II Aldolase and Adducin N-terminal domain
112Diacylglycerol kinase accessory domain
134Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
11Fes/CIP4, and EFC/F-BAR homology domain
157287IQ calmodulin-binding motif
123Phosphoinositide 3-kinase family, accessory domain (PIK domain)
11Regulator of G protein signaling domain
123GTPase-activator protein for Ras-like GTPase
112RasGEF domain
11RasGEF N-terminal motif
358RhoGAP domain
325RhoGEF domain
221941SPRY domain
235RNA polymerase Rpb1, domain 2
6612Guanylate kinase
7512Gelsolin repeat
112839UBA/TS-N domain
112536PHD-finger
11MAM domain, meprin/A5/mu
182038Filamin/ABP280 repeat
162541HECT-domain (ubiquitin-transferase)
156Helix-hairpin-helix motif
11BRCA2 repeat
325MSP (Major sperm protein) domain
22Ribonuclease III domain
448Region in Clathrin and VPS
246RanBP1 domain
5510PPIC-type PPIASE domain
9817Zn-finger in Ran binding protein and others
162743Zinc finger C-x8-C-x5-C-x3-H type (and similar)
639B-box zinc finger
132336Poly(ADP-ribose) polymerase catalytic domain
415Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
52025F-box domain
71017Calpain family cysteine protease
162440CRAL/TRIO domain
81422BTB/POZ domain
33Ricin-type beta-trefoil lectin domain
51217Inhibitor of Apoptosis domain
10818Voltage gated chloride channel
11920Caspase domain
33GDSL-like Lipase/Acylhydrolase
224Poly-adenylate binding protein, unique domain
123POLO box duplicated region
252550ABC transporter transmembrane region
22Integrase core domain
167FAD binding domain
33Condensation domain
112S-adenosyl-L-homocysteine hydrolase, NAD binding domain
22HAMP domain
112ribosomal L5P family C-terminus
81220Insulinase (Peptidase family M16)
6612Dehydrogenase E1 component
123Lumazine binding domain
7916Elongation factor G C-terminus
347HMGL-like
2911DnaJ central domain
4812Sulfotransferase domain
71421Starch binding domain
325Ribosomal protein L1p/L10e family
81018Cation transporting ATPase, C-terminus
91221Cation transporter/ATPase, N-terminus
123dUTPase
112Aconitase C-terminal domain
4812Amino acid kinase family
213Acyl transferase domain
11Urease beta subunit
123Dihydrodipicolinate synthetase family
124153haloacid dehalogenase-like hydrolase
44Glycosyl hydrolases family 2
11Glycosyl hydrolases family 18
213Proliferating cell nuclear antigen, N-terminal domain
123Translation initiation factor IF-3, C-terminal domain
22Acylphosphatase
112Adenylosuccinate synthetase
112Asparaginase, N-terminal
156Peptidase S24-like
415Inorganic pyrophosphatase
11NADH:flavin oxidoreductase / NADH oxidase family
2243-hydroxyacyl-CoA dehydrogenase, C-terminal domain
246Glycosyl hydrolase family 20, catalytic domain
336HhH-GPD superfamily base excision DNA repair protein
213AIR carboxylase
347GMC oxidoreductase
347Asparagine synthase
123Septin
11EF-1 guanine nucleotide exchange domain
224Homoserine dehydrogenase
22Flavin-binding monooxygenase-like
123Glutamyl-tRNAGlu reductase, dimerisation domain
5611tRNA synthetases class I (E and Q), catalytic domain
224tRNA synthetases class I (R)
347XPG N-terminal domain
91524Metallo-beta-lactamase superfamily
211233F5/8 type C domain
13821Choline/Carnitine o-acyltransferase
224Putative esterase
11Glycosyl hydrolase family 9
325Ferrochelatase
448Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
213Arginosuccinate synthase
213Electron transfer flavoprotein FAD-binding domain
213D-alanyl-D-alanine carboxypeptidase
549RNB domain
11Dioxygenase
134Glycosyltransferase family 29 (sialyltransferase)
11CNH domain
279Diacylglycerol kinase catalytic domain
435194Dual specificity phosphatase, catalytic domain
257P21-Rho-binding domain
132942PX domain
31114UBX domain
123VHS domain
11Phosphoinositide 3-kinase C2
246DAHP synthetase I family
336Carbon-nitrogen hydrolase
11N-acetyltransferase
112Prephenate dehydratase
336Syntaxin
14721Pentapeptide repeats (8 copies)
134Pumilio-family RNA binding repeat
4711Histone-like transcription factor (CBF/NF-Y) and archaeal histone
224Pterin binding enzyme
22ER lumen protein retaining receptor
22Glycoprotease family
112Histidinol dehydrogenase
11H-NS histone family
448impB/mucB/samB family
11
112Ribosomal L15
516Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
112Ribosomal prokaryotic L21 protein
224Ribosomal L28 family
134Ribosomal L29 protein
213Ribosomal L39 protein
112Ribosomal S17
336Ribulose-phosphate 3 epimerase family
112Translationally controlled tumour protein
11Cysteine rich repeat
11Alanine racemase, C-terminal domain
7613AP2 domain
162440RNA pseudouridylate synthase
111223Histone deacetylase domain
11617Glycosyltransferase family 10 (fucosyltransferase) C-term
4610PWWP domain
315788SET domain
224Isochorismatase family
213Amiloride-sensitive sodium channel
448Permease family
112Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
336XPG I-region
112Acetokinase family
11AcrB/AcrD/AcrF family
257DNA photolyase
134Cation-independent mannose-6-phosphate receptor repeat
11Nitroreductase family
549Cytosol aminopeptidase family, catalytic domain
1126,7-dimethyl-8-ribityllumazine synthase
112Ribosomal protein S16
6410Acyl CoA binding protein
7512Cullin family
11Elongation factor TS
448FAD binding domain
11O-methyltransferase domain
91524EamA-like transporter family
224Small Multidrug Resistance protein
22
91120ThiF family
112Ribosomal family S4e
21012Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
212647Ammonium Transporter Family
11RNA helicase
145Sulfate permease family
134MATH domain
246Uncharacterized protein family UPF0004
123Dehydratase family
235Transaldolase/Fructose-6-phosphate aldolase
123Mechanosensitive ion channel
325GTP cyclohydrolase II
1123,4-dihydroxy-2-butanone 4-phosphate synthase
5510Adaptor complexes medium subunit family
12820Exonuclease
112Dipeptidyl peptidase IV (DPP IV) N-terminal region
88NB-ARC domain
11Glycosyl hydrolase family 3 N terminal domain
224Ribosomal protein L44
112Sodium:sulfate symporter transmembrane region
112DNA-dependent RNA polymerase
112FAD binding domain in molybdopterin dehydrogenase
112Glycosyl transferase family 4
224HCO3- transporter family
426Nucleosome assembly protein (NAP)
358Synaptobrevin
11GMP synthase C terminal domain
325Adenosine/AMP deaminase
426Oxidoreductase FAD-binding domain
224Histidine biosynthesis protein
44Glycosyltransferase family 20
156UDP-glucose/GDP-mannose dehydrogenase family, central domain
224Carbamoyl-phosphate synthase small chain, CPSase domain
6814PAS fold
11Diguanylate cyclase, GGDEF domain
178Probable molybdopterin binding domain
6814Sec1 family
426GDP dissociation inhibitor
101121Sodium/hydrogen exchanger family
224RNA polymerase Rpb3/RpoA insert domain
11Inward rectifier potassium channel transmembrane domain
437Initiation factor 2 subunit family
235PQQ enzyme repeat
224Electron transfer flavoprotein domain
213Uricase
112Ribosomal S3Ae family
112Ribosomal L27 protein
224GTP1/OBG
213Gamma-glutamyltranspeptidase
112Ribosomal L40e family
224GrpE
112TatD related DNase
257Inhibitor of apoptosis-promoting Bax1
11Eukaryotic DNA topoisomerase I, catalytic core
11NusB family
11Receptor L domain
639Dynamin central region
1126-O-methylguanine DNA methyltransferase, DNA binding domain
264066Bacteriorhodopsin-like protein
336Carboxyl transferase domain
4711UbiA prenyltransferase family
336DegT/DnrJ/EryC1/StrS aminotransferase family
235Endoribonuclease L-PSP
112SecA preprotein cross-linking domain
11MarR family
22Phosphorylase superfamily
6713Cys/Met metabolism PLP-dependent enzyme
336Glycosyl hydrolases family 31
92534ABC-2 type transporter
99Bestrophin, RFP-TM, chloride channel
347Amino-transferase class IV
369CDP-alcohol phosphatidyltransferase
336Calpain large subunit, domain III
347ATP dependent DNA ligase domain
112FMN-dependent dehydrogenase
224Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
2463-beta hydroxysteroid dehydrogenase/isomerase family
11Glycosyl hydrolases family 38 N-terminal domain
123Nitrite and sulphite reductase 4Fe-4S domain
11Magnesium chelatase, subunit ChlI
22Hint module
11Presenilin
123KDPG and KHG aldolase
11Copper type II ascorbate-dependent monooxygenase, N-terminal domain
112Ribosomal protein S18
11Clathrin light chain
336Ubiquitin carboxyl-terminal hydrolase, family 1
112Ribosomal protein S19e
112Ribosomal protein S6e
178Receptor family ligand binding region
347Transcription factor S-II (TFIIS)
22Surface antigen
347emp24/gp25L/p24 family/GOLD
336NifU-like domain
123Cyclin-dependent kinase regulatory subunit
448Asparaginase
11Dihydrodipicolinate reductase, N-terminus
112F-actin capping protein, beta subunit
224Fructose-bisphosphate aldolase class-II
224Semialdehyde dehydrogenase, NAD binding domain
123DNA mismatch repair protein, C-terminal domain
325Alpha-L-fucosidase
123Dephospho-CoA kinase
336MAPEG family
112G10 protein
224Heme oxygenase
112-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
77NAD:arginine ADP-ribosyltransferase
347DNA topoisomerase
22Elongation factor P (EF-P) OB domain
112Enhancer of rudimentary
11Glucose inhibited division protein A
224Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
112Peptidase family U32
628RNA 3'-terminal phosphate cyclase
89173' exoribonuclease family, domain 1
527tRNA-splicing ligase RtcB
1910tRNA pseudouridine synthase D (TruD)
4812SPFH domain / Band 7 family
358Cytidylyltransferase family
336Formamidopyrimidine-DNA glycosylase N-terminal domain
336GDA1/CD39 (nucleoside phosphatase) family
9615GNS1/SUR4 family
11Bacterial-like globin
112Hydroxymethylglutaryl-coenzyme A synthase N terminal
527Inosine-uridine preferring nucleoside hydrolase
112Ribosomal protein L21e
112Ribosomal protein L36e
213Ribosomal protein L6e
112Phosphatidylethanolamine-binding protein
347RIO1 family
123Ribosomal protein S21
134Tub family
336Alanine racemase, N-terminal domain
325Uncharacterized protein family UPF0016
257Putative RNA methylase family UPF0020
246PP-loop family
224Shwachman-Bodian-Diamond syndrome (SBDS) protein
11SNO glutamine amidotransferase family
336Translation initiation factor 1A / IF-1
11Asp/Glu/Hydantoin racemase
112Dihydroorotate dehydrogenase
44Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
11GPR1/FUN34/yaaH family
123Macrophage migration inhibitory factor (MIF)
11
14152916S rRNA methyltransferase RsmB/F
123RNA polymerase Rpb5, C-terminal domain
123RNA polymerase Rpb6
235RNA polymerase Rpb3/Rpb11 dimerisation domain
224RNA polymerases N / 8 kDa subunit
11Peptidyl-tRNA hydrolase
213Ribosomal protein L17
112Ribosomal protein L31e
112Ribosomal protein L34e
112Ribosomal protein S28e
123Ribosomal protein S8e
437Shikimate kinase
224Uncharacterized protein family UPF0029
141125Dihydrouridine synthase (Dus)
235Uroporphyrinogen decarboxylase (URO-D)
123ubiE/COQ5 methyltransferase family
459NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
224Beta-eliminating lyase
325Adenylate cyclase associated (CAP) N terminal
123Casein kinase II regulatory subunit
112Cytochrome c oxidase subunit Vb
5712Clathrin adaptor complex small chain
134Coproporphyrinogen III oxidase
246Dynein light chain type 1
224Ergosterol biosynthesis ERG4/ERG24 family
11DNA/RNA non-specific endonuclease
112Formate/nitrite transporter
213GTP cyclohydrolase I
279HIT domain
112Indoleamine 2,3-dioxygenase
11Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
459Oxysterol-binding protein
11Phosphomannose isomerase type I
112Protein prenyltransferase alpha subunit repeat
116-pyruvoyl tetrahydropterin synthase
325Pyridoxamine 5'-phosphate oxidase
112Ribosomal protein L19
224Ribosomal protein L24e
112Ribosomal protein L35Ae
8816Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
112Ribosomal protein S21e
11Ribosomal protein S6
224Ribosomal protein S7e
459Translation initiation factor SUI1
224Putative undecaprenyl diphosphate synthase
11Carbohydrate kinase
11Thioredoxin-like [2Fe-2S] ferredoxin
112SAICAR synthetase
11Xylose isomerase-like TIM barrel
325Alanine dehydrogenase/PNT, C-terminal domain
246Aldose 1-epimerase
112Chorismate synthase
224Cytochrome c/c1 heme lyase
71825FAD dependent oxidoreductase
11F-actin capping protein alpha subunit
112Formate--tetrahydrofolate ligase
112Fibrillarin
314Malate synthase
11Orn/Lys/Arg decarboxylase, major domain
112Ribosomal protein L19e
224Ribosomal protein L9, N-terminal domain
213Ribosomal protein S24e
213Ribosomal protein S26e
224Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
117,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
224Phosphoenolpyruvate carboxykinase
112Ribosomal protein L13e
123Telomere recombination
11Glycosyl hydrolases family 35
4610CAP-Gly domain
22
11LacY proton/sugar symporter
11Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
11Creatinase/Prolidase N-terminal domain
224DSBA-like thioredoxin domain
459Pyruvate phosphate dikinase, PEP/pyruvate binding domain
11Polypeptide deformylase
213Pterin 4 alpha carbinolamine dehydratase
123mRNA capping enzyme, catalytic domain
81725OB-fold nucleic acid binding domain
325Peptidase family S49
175875Kelch motif
11Domain of unknown function DUF11
213Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
11Lipoprotein amino terminal region
235Ribonuclease HII
33Poly A polymerase regulatory subunit
11Tautomerase enzyme
151126FYVE zinc finger
8412RIH domain
1125'-3' exonuclease, C-terminal SAM fold
11DHH family
4711Sec7 domain
163046NAD dependent epimerase/dehydratase family
336Glycosyl hydrolase family 14
112Porphobilinogen deaminase, dipyromethane cofactor binding domain
224SIS domain
123Helix-turn-helix
5611Phosphate transporter family
11Ribosomal L25p family
459ARID/BRIGHT DNA binding domain
4261103Collagen triple helix repeat (20 copies)
11Fz domain
11Clathrin propeller repeat
22Topoisomerase DNA binding C4 zinc finger
7916JAB1/Mov34/MPN/PAD-1 ubiquitin protease
91524PCI domain
235tRNA synthetases class I (C) catalytic domain
358Oxidoreductase family, NAD-binding Rossmann fold
437tRNA synthetases class II core domain (F)
213tRNA synthetases class II (A)
3811Putative GTPase activating protein for Arf
11Delta serrate ligand
459tRNA pseudouridine synthase
224ENTH domain
33NF-X1 type zinc finger
141529LSM domain
437R3H domain
448Amidase
1910BAH domain
459AN1-like Zinc finger
11Hsp33 protein
131730Peptidase family M13
549Peptidase family M3
5510Peptidase family M1 domain
5510Peptidase family M41
235Peptidase family M48
183149NHL repeat
112Plexin repeat
11ELM2 domain
112Acetohydroxy acid isomeroreductase, catalytic domain
538Low molecular weight phosphotyrosine protein phosphatase
55D-mannose binding lectin
112MAGE family
11Mucin-like glycoprotein
415Leishmanolysin
437Eukaryotic porin
11Transglycosylase SLT domain
123GRIP domain
224Skp1 family, dimerisation domain
437Cytidylyltransferase-like
11Pentapeptide repeats (8 copies)
112Putative peptidoglycan binding domain
167PUA domain
11Ferric uptake regulator family
184866LysM domain
246PLAT/LH2 domain
5914S4 domain
213PWI domain
11Proprotein convertase P-domain
538IBR domain, a half RING-finger domain
11K-box region
123Type I 3-dehydroquinase
235Shikimate / quinate 5-dehydrogenase
81624Transmembrane amino acid transporter protein
11Frataxin-like domain
325GXGXG motif
13619FAD binding domain
538V-type ATPase 116kDa subunit family
213Periplasmic binding protein
41418Glycosyl transferase family 8
11Phosphoribosyl-AMP cyclohydrolase
11Phosphoribosyl-ATP pyrophosphohydrolase
369Phosphatidylinositol-4-phosphate 5-Kinase
4913Phosphoadenosine phosphosulfate reductase family
224TruB family pseudouridylate synthase (N terminal domain)
11Respiratory-chain NADH dehydrogenase 51 Kd subunit
134ATP-NAD kinase
11Phosphate acetyl/butaryl transferase
235Iron-sulphur cluster biosynthesis
22Polysaccharide deacetylase
131528DHHC palmitoyltransferase
437Glycosyl transferase family 11
9514Glycosyl hydrolase family 47
73340PPR repeat
11Adenosylmethionine decarboxylase
22GIY-YIG catalytic domain
66CorA-like Mg2+ transporter protein
31013Cation efflux family
347Peptidase family M20/M25/M40
246ShK domain-like
134Peptidase family M23
61319Acyltransferase
61218MatE
22DNA methylase
71522DnaJ C terminal domain
123Fumarylacetoacetate (FAA) hydrolase family
11Pyruvate ferredoxin/flavodoxin oxidoreductase
224Spermine/spermidine synthase domain
6713FAD binding domain
145Natural resistance-associated macrophage protein
459PAP2 superfamily
246Aminomethyltransferase folate-binding domain
11MaoC like domain
112Adenylylsulphate kinase
9918G-patch domain
5611Putative tRNA binding domain
51318GAF domain
3476-phosphofructo-2-kinase
112NifU-like N terminal domain
71421Flavin containing amine oxidoreductase
22AI-2E family transporter
44Cyclin M transmembrane N-terminal domain
145O-methyltransferase
112Glycine cleavage H-protein
33
213Ribosomal protein S27a
101121Adaptin N terminal region
112Protein phosphatase 2A regulatory B subunit (B56 family)
11Transposase DDE domain
78153'-5' exonuclease
22Flavin reductase like domain
112Proline dehydrogenase
358MutS domain I
6612Peptide methionine sulfoxide reductase
11Hpt domain
112Ribosomal protein L35
123Choline/ethanolamine kinase
213ATP phosphoribosyltransferase
527Phosphotransferase enzyme family
5712SelR domain
112Methylmalonyl-CoA mutase
224Conserved region in glutamate synthase
1234'-phosphopantetheinyl transferase superfamily
325Peptidase C13 family
358Eukaryotic initiation factor 4E
112Ribosomal protein L32
112Myo-inositol-1-phosphate synthase
112Macro domain
213Type I phosphodiesterase / nucleotide pyrophosphatase
112Ribosomal protein S27
11SmpB protein
213Metalloenzyme superfamily
112Diaminopimelate epimerase
112SOR/SNZ family
123Riboflavin kinase
11Caulimovirus viroplasmin
71017Rhomboid family
3710Glycosyltransferase family 92
21012Sodium/calcium exchanger protein
325Queuine tRNA-ribosyltransferase
246UTP--glucose-1-phosphate uridylyltransferase
22Transcriptional regulator
235Deoxynucleoside kinase
134Smr domain
112IPP transferase
112Manganese-stabilising protein / photosystem II polypeptide
257BolA-like protein
213Ham1 family
13922FtsJ-like methyltransferase
213Quinolinate phosphoribosyl transferase, C-terminal domain
11Nucleoside transporter
101525Patatin-like phospholipase
22Dienelactone hydrolase family
11CheR methyltransferase, SAM binding domain
22STAS domain
11Poly A polymerase head domain
123tRNA (Guanine-1)-methyltransferase
123ATP-sulfurylase
11Importin beta binding domain
156Toprim domain
90797MYND finger
11A20-like zinc finger
33Glycosyltransferase family 25 (LPS biosynthesis protein)
11Acyl-CoA oxidase
11Acyltransferase family
459Sodium Bile acid symporter family
1123-dehydroquinate synthase
112Galactosyltransferase
71522Lipase (class 3)
123Ribosome recycling factor
11Divalent cation transporter
112Na+ dependent nucleoside transporter N-terminus
11UreD urease accessory protein
314Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
224Ribosomal L22e protein family
112Ribosomal L27e protein family
213Ribosomal L28e protein family
224Ribosomal L29e protein family
112Ribosomal L37ae protein family
123Ribosomal L38e protein family
112Ribosomal L32p protein family
11NIF3 (NGG1p interacting factor 3)
3710Alternative oxidase
44PsbP
123DeoC/LacD family aldolase
145Glycolipid 2-alpha-mannosyltransferase
11Ferric reductase like transmembrane component
112MraW methylase family
134snoRNA binding domain, fibrillarin
112[2Fe-2S] binding domain
156Surp module
112AICARFT/IMPCHase bienzyme
112Putative membrane protein insertion efficiency factor
1235-formyltetrahydrofolate cyclo-ligase family
112ATP synthase subunit D
123Hemerythrin HHE cation binding domain
112Chorismate mutase type II
415GPCR proteolysis site, GPS, motif
11Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
10361164IPT/TIG domain
145FG-GAP repeat
123Transglutaminase-like superfamily
246ACT domain
336HNH endonuclease
336FF domain
246NAC domain
235Proteasome/cyclosome repeat
178START domain
235MOZ/SAS family
11Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
213Retinoblastoma-associated protein B domain
325Putative diphthamide synthesis protein
11Domain of unknown function UPF0086
112BadF/BadG/BcrA/BcrD ATPase family
112AMMECR1
224RibD C-terminal domain
235Domain found in IF2B/IF5
11Memo-like protein
11RNase P subunit p30
112EVE domain
336Iron-sulfur cluster assembly protein
11RNA 2'-phosphotransferase, Tpt1 / KptA family
112Uncharacterised protein family UPF0047
112DNA primase small subunit
33Rpp14/Pop5 family
112Diphthamide synthase
11CbiX
112Ribosomal protein L37e
459Nucleotidyltransferase domain
112eIF-6 family
11Glycosyl hydrolase family 3 C-terminal domain
11Deoxyhypusine synthase
112Alba
459Prefoldin subunit
112SRP19 protein
112Cobalamin adenosyltransferase
516Sulfite exporter TauE/SafE
19294850S ribosome-binding GTPase
11Mut7-C RNAse domain
112Ribosomal protein L14
112Protein of unknown function DUF84
11Uncharacterised protein family UPF0052
718NYN domain
22Protein of unknown function DUF89
235TRAM domain
22Integral membrane protein DUF92
22Thi4 family
11Archease protein family (MTH1598/TM1083)
11Adenosylcobinamide amidohydrolase
11Integral membrane protein EMC3/TMCO1-like
257TraB family
347DJ-1/PfpI family
448HD domain
11MoaC family
11Hydantoinase/oxoprolinase
11tRNA intron endonuclease, catalytic C-terminal domain
21012Amidohydrolase family
145tRNA-methyltransferase O
224Peptidyl-tRNA hydrolase PTH2
123Double-stranded DNA-binding domain
11CRS1 / YhbY (CRM) domain
167Mitochondrial biogenesis AIM24
112ATP synthase (F/14-kDa) subunit
112ATP synthase (E/31 kDa) subunit
112ATP synthase (C/AC39) subunit
11Translin family
112TFIIE alpha subunit
235N2,N2-dimethylguanosine tRNA methyltransferase
231235REJ domain
77BNR/Asp-box repeat
213eIF4-gamma/eIF5/eIF2-epsilon
156BCCT, betaine/carnitine/choline family transporter
123Ribosome-binding factor A
202747SAP domain
110217327RWP-RK domain
167Melibiase
22Aromatic-di-Alanine (AdAR) repeat
33Carboxypeptidase Taq (M32) metallopeptidase
11D12 class N6 adenine-specific DNA methyltransferase
213Palmitoyl protein thioesterase
34760Kd inner membrane protein
112Josephin
33Hydroxyethylthiazole kinase family
112Phosducin
11RHO protein GDP dissociation inhibitor
459Phosphatidylinositol transfer protein
11Phosphotriesterase family
112Aminopeptidase I zinc metalloprotease (M18)
11X-Pro dipeptidyl-peptidase (S15 family)
112Uncharacterized protein family UPF0054
257
336Nuclear transport factor 2 (NTF2) domain
325Adenosine-deaminase (editase) domain
5712Beige/BEACH domain
134DENN (AEX-3) domain
123MGS-like domain
112Repair protein Rad1/Rec1/Rad17
11Rap/ran-GAP
369Sir2 family
325Zn-finger in ubiquitin-hydrolases and other protein
11RNA polymerases M/15 Kd subunit
459UvrB/uvrC motif
11Dihydroneopterin aldolase
11Prephenate dehydrogenase
11Flagellar motor switch protein FliM
224Peptidase family M50
112Cytochrome C1 family
11PAZ domain
42143TRAF-type zinc finger
145AT hook motif
3710Formin Homology 2 Domain
11Homeobox associated leucine zipper
11HAT (Half-A-TPR) repeat
314ATP-dependent protease La (LON) substrate-binding domain
11PXA domain
11ParB-like nuclease domain
347Regulatory subunit of type II PKA R-subunit
224SWIB/MDM2 domain
145Vacuolar sorting protein 9 (VPS9) domain