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PFAM Domains • Rhizaria
Annotations/GenomesBigna1Retfil1TotalAnnotation Description
117 transmembrane receptor (rhodopsin family)
117 transmembrane receptor (Secretin family)
1112237 transmembrane sweet-taste receptor of 3 GCPR
5779136ATPase family associated with various cellular activities (AAA)
8976165ABC transporter
5611ATP synthase alpha/beta family, nucleotide-binding domain
9110EGF-like domain
292958Elongation factor Tu GTP binding domain
55Helix-loop-helix DNA-binding domain
15217Hsp20/alpha crystallin family
155671Hsp70 protein
21829KH domain
44SH2 domain
291039SH3 domain
22TNFR/NGFR cysteine-rich region
35241393Ankyrin repeat
99PAN domain
222042ADP-ribosylation factor family
211536Eukaryotic aspartyl protease
365591Cyclic nucleotide-binding domain
11Cystatin domain
213Cytochrome c
112Double-stranded RNA binding motif
27516291EF hand
224Fe-4S binding domain
10818Fibronectin type III domain
24933Glutathione S-transferase, C-terminal domain
415Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
11Kringle domain
11Laminin EGF domain
358lactate/malate dehydrogenase, NAD binding domain
22Low-density lipoprotein receptor domain class A
527Lectin C-type domain
252045Myosin head (motor domain)
11LNR domain
162036Cytochrome P450
329563892Protein kinase domain
181129Pyridine nucleotide-disulphide oxidoreductase
75178253Ras family
77Response regulator receiver domain
22426RNase H
114107221RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
22Retroviral aspartyl protease
6868Reverse transcriptase (RNA-dependent DNA polymerase)
1313Serpin (serine protease inhibitor)
213Copper/zinc superoxide dismutase (SODC)
224Iron/manganese superoxide dismutases, alpha-hairpin domain
639Subtilase family
26935Sugar (and other) transporter
22Trefoil (P-type) domain
7310Thrombospondin type 1 domain
138699Tubulin/FtsZ family, GTPase domain
12416von Willebrand factor type A domain
224von Willebrand factor type D domain
10731138Zinc finger, C2H2 type
9414108Zinc finger, C3HC4 type (RING finger)
9514Zinc knuckle
22Ribulose bisphosphate carboxylase, small chain
123Protein-tyrosine phosphatase
6347110short chain dehydrogenase
191231Zinc-binding dehydrogenase
5712Thiolase, N-terminal domain
415Beta-ketoacyl synthase, N-terminal domain
143172Fe-2S iron-sulfur cluster binding domain
271138Papain family cysteine protease
448Enolase, C-terminal TIM barrel domain
91019Glutamine amidotransferase class-I
142943TCP-1/cpn60 chaperonin family
628Glutamine synthetase, catalytic domain
516Triosephosphate isomerase
222345E1-E2 ATPase
22931Core histone H2A/H2B/H3/H4
325Alpha amylase, catalytic domain
22Phorbol esters/diacylglycerol binding domain (C1 domain)
9514Bacterial transferase hexapeptide (six repeats)
11920tRNA synthetases class I (I, L, M and V)
161228Cyclin, N-terminal domain
17724Carboxylesterase family
639DNA polymerase family B
336ATP synthase subunit C
33Legume lectin domain
415C-5 cytosine-specific DNA methylase
22Fibrinogen beta and gamma chains, C-terminal globular domain
6443107Calcineurin-like phosphoesterase
527Cellulase (glycosyl hydrolase family 5)
11718tRNA synthetases class II (D, K and N)
6945114Mitochondrial carrier protein
172138Aminotransferase class I and II
9615Phosphoribosyl transferase domain
421254Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
729Phosphoglycerate kinase
224Ribosomal protein S4/S9 N-terminal domain
123Ribosomal protein S12/S23
33Chaperonin 10 Kd subunit
5557112C2 domain
9484178PH domain
426bZIP transcription factor
112738Aldehyde dehydrogenase family
2424Fungal Zn(2)-Cys(6) binuclear cluster domain
251237Cytochrome b5-like Heme/Steroid binding domain
314Oxidoreductase molybdopterin binding domain
101020Oxidoreductase NAD-binding domain
423274SNF2 family N-terminal domain
213Ribosomal protein S7p/S5e
322961Ubiquitin-conjugating enzyme
268Isocitrate/isopropylmalate dehydrogenase
213Ribosomal Proteins L2, RNA binding domain
33033Hsp90 protein
246Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
314Dihydrofolate reductase
347Cysteine-rich secretory protein family
112Ribosomal protein S3, C-terminal domain
88Eukaryotic-type carbonic anhydrase
11Chalcone and stilbene synthases, N-terminal domain
5492-oxoacid dehydrogenases acyltransferase (catalytic domain)
11UDP-glucoronosyl and UDP-glucosyl transferase
7714Aminotransferase class-III
246Ribosomal protein S19
325DNA gyrase B
123Thiamine pyrophosphate enzyme, central domain
279Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
43236Adenylate and Guanylate cyclase catalytic domain
213ATP synthase delta (OSCP) subunit
112Orotidine 5'-phosphate decarboxylase / HUMPS family
235ATP:guanido phosphotransferase, C-terminal catalytic domain
11Indole-3-glycerol phosphate synthase
11Aromatic amino acid lyase
819Pyruvate kinase, barrel domain
8097177Kinesin motor domain
8039119DnaJ domain
152136Proteasome subunit
8412Major intrinsic protein
325ATP synthase
22Glycosyl hydrolase family 1
1030403'5'-cyclic nucleotide phosphodiesterase
325Ribosomal protein L22p/L17e
112Ribosomal protein L14p/L23e
6164125Ubiquitin family
6612Cofilin/tropomyosin-type actin-binding protein
8101814-3-3 protein
11Alkaline phosphatase
10111Zinc carboxypeptidase
412667Aldo/keto reductase family
39544Myb-like DNA-binding domain
33Glycosyl hydrolases family 32 N-terminal domain
11Ribosomal protein L16p/L10e
33Ribosomal protein S14p/S29e
411859FKBP-type peptidyl-prolyl cis-trans isomerase
6410Glutathione peroxidase
123Calreticulin family
11Bacterial type II and III secretion system protein
235Common central domain of tyrosinase
22Thymidine kinase
11920Aminotransferase class-V
14216Ribonucleotide reductase, small chain
9377170DEAD/DEAH box helicase
14089229Helicase conserved C-terminal domain
325Fructose-bisphosphate aldolase class-I
44EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
224Ribosomal protein L23
415Pyridoxal-dependent decarboxylase, C-terminal sheet domain
11Ribosomal protein L5
246Pyridoxal-dependent decarboxylase conserved domain
3912Citrate synthase, C-terminal domain
7613GHMP kinases N terminal domain
729Biotin carboxylase, N-terminal domain
11Tryptophan synthase alpha chain
16420Pyridoxal-phosphate dependent enzyme
291847NUDIX domain
81018pfkB family carbohydrate kinase
66Glycosyl hydrolases family 28
314Ribosomal protein L3
33Ribosomal protein L11, RNA binding domain
412263Histidine phosphatase superfamily (branch 1)
213Thymidylate synthase
347ATP synthase alpha/beta chain, C terminal domain
152237Calponin homology (CH) domain
55Glutamine amidotransferases class-II
11Phosphoenolpyruvate carboxylase
44Ribosomal protein S15
13316'Cold-shock' DNA-binding domain
314Thaumatin family
6410Fructose-1-6-bisphosphatase, N-terminal domain
224Ribonucleotide reductase, all-alpha domain
123Ribosomal protein S2
22SRF-type transcription factor (DNA-binding and dimerisation domain)
111930Amino acid permease
8614Prolyl oligopeptidase family
112Ribosomal protein L30p/L7e
7714Histidine phosphatase superfamily (branch 2)
11Respiratory-chain NADH dehydrogenase, 30 Kd subunit
415Aconitase family (aconitate hydratase)
224Ribosomal protein S5, N-terminal domain
6410Nucleoside diphosphate kinase
369Tetraspanin family
33Galactoside-binding lectin
22Ribosomal protein S10p/S20e
22Arrestin (or S-antigen), N-terminal domain
314Phosphoglucose isomerase
145SecY translocase
314Ribosomal protein L6
628Polyprenyl synthetase
51015Dynamin family
123Biopterin-dependent aromatic amino acid hydroxylase
213Transcription factor TFIID (or TATA-binding protein, TBP)
11RTX calcium-binding nonapeptide repeat (4 copies)
9615Rieske [2Fe-2S] domain
13316Biotin-requiring enzyme
224Ribosomal protein S17
11Hydroxymethylglutaryl-coenzyme A reductase
437FGGY family of carbohydrate kinases, N-terminal domain
22FERM central domain
112Sodium:dicarboxylate symporter family
121426Enoyl-CoA hydratase/isomerase
325Ribosomal protein S9/S16
336Transcription factor TFIIB repeat
12517Cytidine and deoxycytidylate deaminase zinc-binding region
112Molybdopterin oxidoreductase
101727Chromo (CHRromatin Organisation MOdifier) domain
11Phosphatidylinositol-specific phospholipase C, Y domain
22Phosphatidylinositol-specific phospholipase C, X domain
235D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
224Malic enzyme, N-terminal domain
22PEP-utilising enzyme, mobile domain
2136-phosphogluconate dehydrogenase, C-terminal domain
11Multicopper oxidase
621375WW domain
314Ribosomal RNA adenine dimethylase
2022,5252,727WD domain, G-beta repeat
426Heavy-metal-associated domain
91322Adenylate kinase
314Phosphoglucomutase/phosphomannomutase, C-terminal domain
112Ribosomal protein S8
112Ribosomal protein S11
459LIM domain
262349Regulator of chromosome condensation (RCC1) repeat
325Ribosomal protein S13/S18
33chorismate binding enzyme
45960s Acidic ribosomal protein
11ATP synthase B/B' CF(0)
11CUB domain
426Prenyltransferase and squalene oxidase repeat
4913Protein kinase C terminal domain
11Single-strand binding protein family
224S-adenosylmethionine synthetase, N-terminal domain
11Bacterial regulatory proteins, tetR family
121426Acyl-CoA dehydrogenase, C-terminal domain
47106153Ubiquitin carboxyl-terminal hydrolase
11Ribosomal protein L36
112Ribonuclease T2 family
22HSF-type DNA-binding
538SRP54-type protein, GTPase domain
11Urease alpha-subunit, N-terminal domain
92736Serine carboxypeptidase
112Ribosomal protein L20
273663Phosphatidylinositol 3- and 4-kinase
437Transketolase, thiamine diphosphate binding domain
8715Inositol monophosphatase family
112Isocitrate lyase family
325Serine hydroxymethyltransferase
336Iron-containing alcohol dehydrogenase
213Ribosomal protein L10
426KOW motif
22Ribosomal protein L34
22Ribosomal protein L33
516RF-1 domain
11Sodium:solute symporter family
448DNA polymerase family A
257IMP dehydrogenase / GMP reductase domain
538Glucose-6-phosphate dehydrogenase, NAD binding domain
22ROK family
302151Protein phosphatase 2C
235Nucleotidyl transferase
336Phosphoribulokinase / Uridine kinase family
161127Fatty acid desaturase
71219MutS domain V
235Delta-aminolevulinic acid dehydratase
257Arginase family
8917MCM P-loop domain
213Squalene/phytoene synthase
11Bacterial extracellular solute-binding proteins, family 5 Middle
341145FHA domain
332154AMP-binding enzyme
35128163G-protein alpha subunit
2020Chlorophyll A-B binding protein
36339HMG (high mobility group) box
33His Kinase A (phospho-acceptor) domain
111425Armadillo/beta-catenin-like repeat
93139232Tetratricopeptide repeat
4367110Ion transport protein
314DNA gyrase/topoisomerase IV, subunit A
1010Scavenger receptor cysteine-rich domain
20828BRCA1 C Terminus (BRCT) domain
111021Glycosyl transferases group 1
9312Glycosyl transferase family 2
96271SAM domain (Sterile alpha motif)
213linker histone H1 and H5 family
213Ribosomal protein L7/L12 C-terminal domain
11Urease, gamma subunit
617Phosphopantetheine attachment site
22Formyl transferase
12921Metallopeptidase family M24
12121142Leucine Rich Repeat
41344alpha/beta hydrolase fold
358RNA polymerase Rpb2, domain 6
11EAL domain
11617PB1 domain
3710Staphylococcal nuclease homologue
316899Rab-GTPase-TBC domain
347Tudor domain
213WH1 domain
41115Zinc finger, ZZ type
112HRDC domain
182240CBS domain
314Ribosomal protein L13
325Ribosomal protein L4/L1 family
11Clp protease
17623S1 RNA binding domain
11HIUase/Transthyretin family
7411AhpC/TSA family
6511tRNA synthetases class I (W and Y)
213UvrD/REP helicase N-terminal domain
121729Rhodanese-like domain
11415Universal stress protein family
481866Acetyltransferase (GNAT) family
11SecE/Sec61-gamma subunits of protein translocation complex
11C-terminal regulatory domain of Threonine dehydratase
11AIR synthase related protein, N-terminal domain
13720tRNA synthetase class II core domain (G, H, P, S and T)
17219SpoU rRNA Methylase family
11Phage integrase family
314Tetrapyrrole (Corrin/Porphyrin) Methylases
11Glycosyl transferase family, a/b domain
6915PDZ domain
325Class II Aldolase and Adducin N-terminal domain
66Diacylglycerol kinase accessory domain
194362Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
11Fes/CIP4, and EFC/F-BAR homology domain
21223IQ calmodulin-binding motif
51419Phosphoinositide 3-kinase family, accessory domain (PIK domain)
33Phospholipase D Active site motif
68187Regulator of G protein signaling domain
5914GTPase-activator protein for Ras-like GTPase
74653RasGEF domain
2911RasGEF N-terminal motif
283260RhoGAP domain
314273RhoGEF domain
243559SPRY domain
527RNA polymerase Rpb1, domain 2
459Guanylate kinase
617Gelsolin repeat
51960UBA/TS-N domain
44Filamin/ABP280 repeat
303363HECT-domain (ubiquitin-transferase)
55Helix-hairpin-helix motif
11BRCA2 repeat
55MSP (Major sperm protein) domain
336Ribonuclease III domain
21214Region in Clathrin and VPS
3912RanBP1 domain
426PPIC-type PPIASE domain
392564Zn-finger in Ran binding protein and others
421961Zinc finger C-x8-C-x5-C-x3-H type (and similar)
246B-box zinc finger
61420Poly(ADP-ribose) polymerase catalytic domain
415Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
19726F-box domain
14317Calpain family cysteine protease
271340CRAL/TRIO domain
122234BTB/POZ domain
8210Ricin-type beta-trefoil lectin domain
11Inhibitor of Apoptosis domain
91221Voltage gated chloride channel
7106113Caspase domain
415GDSL-like Lipase/Acylhydrolase
61319Poly-adenylate binding protein, unique domain
134POLO box duplicated region
201838ABC transporter transmembrane region
35944Integrase core domain
358FAD binding domain
11Condensation domain
246S-adenosyl-L-homocysteine hydrolase, NAD binding domain
112ribosomal L5P family C-terminus
14519Insulinase (Peptidase family M16)
6612Dehydrogenase E1 component
11Lumazine binding domain
11819Elongation factor G C-terminus
6410DnaJ central domain
8816Sulfotransferase domain
11Starch binding domain
336Ribosomal protein L1p/L10e family
91322Cation transporting ATPase, C-terminus
13619Cation transporter/ATPase, N-terminus
314Aconitase C-terminal domain
628Amino acid kinase family
11N-(5'phosphoribosyl)anthranilate (PRA) isomerase
112Acyl transferase domain
11Urease beta subunit
213Dihydrodipicolinate synthetase family
462167haloacid dehalogenase-like hydrolase
33Glycosyl hydrolases family 2
6410Glycosyl hydrolases family 18
134Proliferating cell nuclear antigen, N-terminal domain
22Translation initiation factor IF-3, C-terminal domain
112Adenylosuccinate synthetase
123Asparaginase, N-terminal
66Peptidase S24-like
7512Inorganic pyrophosphatase
516Glycosyl hydrolases family 16
112Glycosyl hydrolases family 15
112NADH:flavin oxidoreductase / NADH oxidase family
4483-hydroxyacyl-CoA dehydrogenase, C-terminal domain
448Glycosyl hydrolase family 20, catalytic domain
729HhH-GPD superfamily base excision DNA repair protein
22AIR carboxylase
628GMC oxidoreductase
3710Asparagine synthase
123Homoserine dehydrogenase
31013Flavin-binding monooxygenase-like
11Glutamyl-tRNAGlu reductase, dimerisation domain
5510tRNA synthetases class I (E and Q), catalytic domain
347tRNA synthetases class I (R)
5510XPG N-terminal domain
12921Metallo-beta-lactamase superfamily
77F5/8 type C domain
235Putative esterase
314Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
11Arginosuccinate synthase
112Electron transfer flavoprotein FAD-binding domain
4711RNB domain
11BTK motif
123CNH domain
3912Diacylglycerol kinase catalytic domain
343872Dual specificity phosphatase, catalytic domain
8715MyTH4 domain
33P21-Rho-binding domain
292655PX domain
134Ras association (RalGDS/AF-6) domain
81119UBX domain
235VHS domain
369Phosphoinositide 3-kinase C2
11DAHP synthetase I family
268PI3-kinase family, ras-binding domain
71017Carbon-nitrogen hydrolase
11Geminivirus Rep catalytic domain
33Prephenate dehydratase
38083Pentapeptide repeats (8 copies)
42529Pumilio-family RNA binding repeat
639Histone-like transcription factor (CBF/NF-Y) and archaeal histone
235Pterin binding enzyme
314ER lumen protein retaining receptor
314Glycoprotease family
22Histidinol dehydrogenase
9312impB/mucB/samB family
44Phosphoenolpyruvate carboxykinase C-terminal P-loop domain
123Ribosomal L15
112Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
213Ribosomal prokaryotic L21 protein
22Ribosomal L28 family
213Ribosomal L29 protein
22Ribosomal L39 protein
11Ribosomal S17
314Ribulose-phosphate 3 epimerase family
33Iodothyronine deiodinase
11Glycosyl hydrolase family 7
88AP2 domain
11Ring hydroxylating alpha subunit (catalytic domain)
15823RNA pseudouridylate synthase
141327Histone deacetylase domain
4610Glycosyltransferase family 10 (fucosyltransferase) C-term
3710POT family
224PWWP domain
452772SET domain
426Isochorismatase family
11Permease family
22Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
224ATP P2X receptor
5914XPG I-region
11Acetokinase family
11Transposase, Mutator family
77DNA photolyase
516Nitroreductase family
213Cytosol aminopeptidase family, catalytic domain
116,7-dimethyl-8-ribityllumazine synthase
224Ribosomal protein S16
336Acyl CoA binding protein
91827Cullin family
213Elongation factor TS
5611FAD binding domain
213O-methyltransferase domain
17421EamA-like transporter family
17623ThiF family
123Ribosomal family S4e
8311Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
22dTDP-4-dehydrorhamnose 3,5-epimerase
10717Ammonium Transporter Family
71724Sulfate permease family
11MATH domain
44Uncharacterized protein family UPF0004
123Dehydratase family
516Transaldolase/Fructose-6-phosphate aldolase
347Mechanosensitive ion channel
123GTP cyclohydrolase II
113,4-dihydroxy-2-butanone 4-phosphate synthase
71421Adaptor complexes medium subunit family
123Dipeptidyl peptidase IV (DPP IV) N-terminal region
819Glycosyl hydrolase family 3 N terminal domain
112Ribosomal protein L44
22Sodium:sulfate symporter transmembrane region
11DNA-dependent RNA polymerase
33FAD binding domain in molybdopterin dehydrogenase
112Glycosyl transferase family 4
44HCO3- transporter family
44Nucleosome assembly protein (NAP)
112GMP synthase C terminal domain
61622Adenosine/AMP deaminase
6511Oxidoreductase FAD-binding domain
11Thioesterase domain
22Histidine biosynthesis protein
437Glycosyltransferase family 20
325UDP-glucose/GDP-mannose dehydrogenase family, central domain
11DNA gyrase B subunit, carboxyl terminus
213Carbamoyl-phosphate synthase small chain, CPSase domain
11PAS fold
22Diguanylate cyclase, GGDEF domain
314Probable molybdopterin binding domain
5914Sec1 family
2911GDP dissociation inhibitor
13417Sodium/hydrogen exchanger family
224RNA polymerase Rpb3/RpoA insert domain
33Inward rectifier potassium channel transmembrane domain
415Initiation factor 2 subunit family
213PQQ enzyme repeat
224Electron transfer flavoprotein domain
123Ribosomal S3Ae family
213Ribosomal L27 protein
3710TatD related DNase
314Inhibitor of apoptosis-promoting Bax1
213Eukaryotic DNA topoisomerase I, catalytic core
369Dynamin central region
11Somatomedin B domain
116-O-methylguanine DNA methyltransferase, DNA binding domain
11Bacteriorhodopsin-like protein
459Carboxyl transferase domain
8210UbiA prenyltransferase family
213DegT/DnrJ/EryC1/StrS aminotransferase family
448Endoribonuclease L-PSP
112SecA preprotein cross-linking domain
358Phosphorylase superfamily
11Mannose-6-phosphate isomerase
527Cys/Met metabolism PLP-dependent enzyme
51217Glycosyl hydrolases family 31
11NADH ubiquinone oxidoreductase, 20 Kd subunit
202040ABC-2 type transporter
11Bestrophin, RFP-TM, chloride channel
448Amino-transferase class IV
448CDP-alcohol phosphatidyltransferase
123Calpain large subunit, domain III
7613ATP dependent DNA ligase domain
112FMN-dependent dehydrogenase
11Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
2573-beta hydroxysteroid dehydrogenase/isomerase family
459Glycosyl hydrolases family 38 N-terminal domain
11Plasmid recombination enzyme
33Nitrite and sulphite reductase 4Fe-4S domain
213Magnesium chelatase, subunit ChlI
235Hint module
112Ribosomal protein S18
33Clathrin light chain
347Ubiquitin carboxyl-terminal hydrolase, family 1
224Ribosomal protein S19e
112Ribosomal protein S6e
33Receptor family ligand binding region
527Transcription factor S-II (TFIIS)
22Surface antigen
7916emp24/gp25L/p24 family/GOLD
426NifU-like domain
33Cyclin-dependent kinase regulatory subunit
134F-actin capping protein, beta subunit
11Fructose-bisphosphate aldolase class-II
112Semialdehyde dehydrogenase, NAD binding domain
123DNA mismatch repair protein, C-terminal domain
224Dephospho-CoA kinase
257MAPEG family
11G10 protein
22Heme oxygenase
11Succinate dehydrogenase/Fumarate reductase transmembrane subunit
112-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
213NAD:arginine ADP-ribosyltransferase
21315CD36 family
347DNA topoisomerase
22Elongation factor P (EF-P) OB domain
11Enhancer of rudimentary
22Glucose inhibited division protein A
549Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
11Peptidase family U32
257RNA 3'-terminal phosphate cyclase
76133' exoribonuclease family, domain 1
134tRNA-splicing ligase RtcB
617tRNA pseudouridine synthase D (TruD)
123Coenzyme A transferase
10717SPFH domain / Band 7 family
448Cytidylyltransferase family
314Formamidopyrimidine-DNA glycosylase N-terminal domain
639GDA1/CD39 (nucleoside phosphatase) family
12719GNS1/SUR4 family
11Bacterial-like globin
11Hydroxymethylglutaryl-coenzyme A synthase N terminal
369Inosine-uridine preferring nucleoside hydrolase
11Ribosomal protein L21e
123Ribosomal protein L36e
112Ribosomal protein L6e
112Phosphatidylethanolamine-binding protein
527RIO1 family
112Tub family
325Alanine racemase, N-terminal domain
33Uncharacterized protein family UPF0016
718Putative RNA methylase family UPF0020
527PP-loop family
358Shwachman-Bodian-Diamond syndrome (SBDS) protein
11SNO glutamine amidotransferase family
22Urocanase Rossmann-like domain
22Translation initiation factor 1A / IF-1
123Asp/Glu/Hydantoin racemase
213Dihydroorotate dehydrogenase
213Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
11Macrophage migration inhibitory factor (MIF)
751216S rRNA methyltransferase RsmB/F
112RNA polymerase Rpb5, C-terminal domain
112RNA polymerase Rpb6
415RNA polymerase Rpb3/Rpb11 dimerisation domain
11RNA polymerases N / 8 kDa subunit
11Peptidyl-tRNA hydrolase
22Ribosomal protein L17
11Ribosomal protein L31
22Ribosomal protein L31e
112Ribosomal protein L34e
213Ribosomal protein S28e
224Ribosomal protein S8e
44Shikimate kinase
213Uncharacterized protein family UPF0029
101020Dihydrouridine synthase (Dus)
516Uroporphyrinogen decarboxylase (URO-D)
44ubiE/COQ5 methyltransferase family
314NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
112Beta-eliminating lyase
134Adenylate cyclase associated (CAP) N terminal
347Casein kinase II regulatory subunit
112Cytochrome c oxidase subunit Vb
10717Clathrin adaptor complex small chain
426Coproporphyrinogen III oxidase
8614Dynein light chain type 1
347Ergosterol biosynthesis ERG4/ERG24 family
123DNA/RNA non-specific endonuclease
11Formate/nitrite transporter
11GTP cyclohydrolase I
11Glycine radical
448HIT domain
213Indoleamine 2,3-dioxygenase
22Mannitol dehydrogenase Rossmann domain
213Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain
11Oxysterol-binding protein
112Phosphomannose isomerase type I
325Protein prenyltransferase alpha subunit repeat
336Pyridoxamine 5'-phosphate oxidase
22Ribosomal protein L19
224Ribosomal protein L24e
22Ribosomal protein L35Ae
7310Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
11Ribosomal protein S21e
112Ribosomal protein S6
123Ribosomal protein S7e
538Translation initiation factor SUI1
11Putative undecaprenyl diphosphate synthase
224Carbohydrate kinase
112Thioredoxin-like [2Fe-2S] ferredoxin
11SAICAR synthetase
336Alanine dehydrogenase/PNT, C-terminal domain
538Aldose 1-epimerase
22Chorismate synthase
325Cytochrome c/c1 heme lyase
291039FAD dependent oxidoreductase
112F-actin capping protein alpha subunit
11Formate--tetrahydrofolate ligase
11Malate synthase
11Orn/Lys/Arg decarboxylase, major domain
123Ribosomal protein L19e
213Ribosomal protein L9, N-terminal domain
11Ribosomal protein S24e
123Ribosomal protein S26e
11Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
11Prokaryotic cytochrome b561
123Phosphoenolpyruvate carboxykinase
213Ribosomal protein L13e
415Telomere recombination
426Glycosyl hydrolases family 35
7124131CAP-Gly domain
33Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
213Creatinase/Prolidase N-terminal domain
246DSBA-like thioredoxin domain
33Pyruvate phosphate dikinase, PEP/pyruvate binding domain
224Polypeptide deformylase
22Pterin 4 alpha carbinolamine dehydratase
246mRNA capping enzyme, catalytic domain
14721OB-fold nucleic acid binding domain
358Peptidase family S49
66159225Kelch motif
22Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
325Ribonuclease HII
11Pollen allergen
22Poly A polymerase regulatory subunit
212950FYVE zinc finger
225'-3' exonuclease, C-terminal SAM fold
112DHH family
51520Sec7 domain
251742NAD dependent epimerase/dehydratase family
213Porphobilinogen deaminase, dipyromethane cofactor binding domain
134SIS domain
426Phosphate transporter family
9413ARID/BRIGHT DNA binding domain
224Collagen triple helix repeat (20 copies)
9817JAB1/Mov34/MPN/PAD-1 ubiquitin protease
151126PCI domain
448tRNA synthetases class I (C) catalytic domain
639Oxidoreductase family, NAD-binding Rossmann fold
437tRNA synthetases class II core domain (F)
336tRNA synthetases class II (A)
182038Putative GTPase activating protein for Arf
538tRNA pseudouridine synthase
4711ENTH domain
11Jacalin-like lectin domain
33Type I restriction modification DNA specificity domain
55Reprolysin (M12B) family zinc metalloprotease
11NF-X1 type zinc finger
18422LSM domain
325R3H domain
22BAH domain
11D-ala-D-ala dipeptidase
527AN1-like Zinc finger
11Methyl-CpG binding domain
11Hsp33 protein
112Peptidase family M13
5510Peptidase family M3
72431Peptidase family M1 domain
549Peptidase family M41
4610Peptidase family M48
6767NHL repeat
11ELM2 domain
11Acetohydroxy acid isomeroreductase, catalytic domain
22Low molecular weight phosphotyrosine protein phosphatase
11MAGE family
22Eukaryotic porin
11Transglycosylase SLT domain
112GRIP domain
5813Skp1 family, dimerisation domain
11Pyroglutamyl peptidase
22Putative peptidoglycan binding domain
336PUA domain
33Class-II DAHP synthetase family
112LysM domain
9312S4 domain
224PWI domain
151227IBR domain, a half RING-finger domain
22Type I 3-dehydroquinase
22Shikimate / quinate 5-dehydrogenase
312253Transmembrane amino acid transporter protein
112Frataxin-like domain
11GXGXG motif
8311FAD binding domain
41317V-type ATPase 116kDa subunit family
10616Glycosyl transferase family 8
11Phosphoribosyl-AMP cyclohydrolase
11Phosphoribosyl-ATP pyrophosphohydrolase
163046Phosphatidylinositol-4-phosphate 5-Kinase
516Phosphoadenosine phosphosulfate reductase family
314TruB family pseudouridylate synthase (N terminal domain)
112Respiratory-chain NADH dehydrogenase 51 Kd subunit
246ATP-NAD kinase
11Phosphate acetyl/butaryl transferase
437Iron-sulphur cluster biosynthesis
11Polysaccharide deacetylase
252045DHHC palmitoyltransferase
82230Glycosyl hydrolase family 47
7235107PPR repeat
112Adenosylmethionine decarboxylase
11Herpesvirus glycoprotein D/GG/GX domain
213GIY-YIG catalytic domain
31114CorA-like Mg2+ transporter protein
101424Cation efflux family
81018Peptidase family M20/M25/M40
145ShK domain-like
213Peptidase family M23
11DNA methylase
81624DnaJ C terminal domain
5712Fumarylacetoacetate (FAA) hydrolase family
22Reprolysin family propeptide
314Spermine/spermidine synthase domain
9615FAD binding domain
22Natural resistance-associated macrophage protein
426PAP2 superfamily
538Aminomethyltransferase folate-binding domain
235MaoC like domain
11TIR domain
224Adenylylsulphate kinase
13518G-patch domain
5611Putative tRNA binding domain
8412GAF domain
11NifU-like N terminal domain
161127Flavin containing amine oxidoreductase
11AI-2E family transporter
6915Cyclin M transmembrane N-terminal domain
22Glycine cleavage H-protein
112Ribosomal protein S27a
112435Adaptin N terminal region
24749Protein phosphatase 2A regulatory B subunit (B56 family)
33Transposase DDE domain
78153'-5' exonuclease
213Proline dehydrogenase
459MutS domain I
9514Peptide methionine sulfoxide reductase
11Hpt domain
11Ribosomal protein L35
235Choline/ethanolamine kinase
11ATP phosphoribosyltransferase
415Phosphotransferase enzyme family
33ATPase domain predominantly from Archaea
7310SelR domain
123Methylmalonyl-CoA mutase
11Conserved region in glutamate synthase
1124'-phosphopantetheinyl transferase superfamily
11Ribosomal protein S20
112Peptidase C13 family
448Eukaryotic initiation factor 4E
11NAD-dependent DNA ligase adenylation domain
11Ribosomal protein L32
167CobQ/CobB/MinD/ParA nucleotide binding domain
123Myo-inositol-1-phosphate synthase
7512Macro domain
66Type I phosphodiesterase / nucleotide pyrophosphatase
11Ribosomal protein S27
22Glycosyl hydrolase family 12
112Diaminopimelate epimerase
112SOR/SNZ family
112Riboflavin kinase
8311Rhomboid family
3912Glycosyltransferase family 92
14822Sodium/calcium exchanger protein
437Queuine tRNA-ribosyltransferase
235UTP--glucose-1-phosphate uridylyltransferase
22Transcriptional regulator
44Deoxynucleoside kinase
22Smr domain
213IPP transferase
11Manganese-stabilising protein / photosystem II polypeptide
44BolA-like protein
213Ham1 family
5813FtsJ-like methyltransferase
112Quinolinate phosphoribosyl transferase, C-terminal domain
145Nucleoside transporter
9514Patatin-like phospholipase
426Dienelactone hydrolase family
5914STAS domain
224Poly A polymerase head domain
235tRNA (Guanine-1)-methyltransferase
2810Importin beta binding domain
437Toprim domain
131124MYND finger
11A20-like zinc finger
1111Glycosyltransferase family 25 (LPS biosynthesis protein)
11Acyl-CoA oxidase
33Acyltransferase family
99Sodium Bile acid symporter family
333-dehydroquinate synthase
251439Lipase (class 3)
213Ribosome recycling factor
123Reduced folate carrier
11UreD urease accessory protein
123Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
123Ribosomal L22e protein family
11Ribosomal L27e protein family
123Ribosomal L28e protein family
112Ribosomal L29e protein family
11Ribosomal L37ae protein family
11Ribosomal L38e protein family
112RimM N-terminal domain
11Ribosomal L32p protein family
213Alternative oxidase
213DeoC/LacD family aldolase
7714Ferric reductase like transmembrane component
11MraW methylase family
448snoRNA binding domain, fibrillarin
44[2Fe-2S] binding domain
22Penicillin amidase
628Surp module
22AICARFT/IMPCHase bienzyme
225-formyltetrahydrofolate cyclo-ligase family
123ATP synthase subunit D
11Hemerythrin HHE cation binding domain
22Chorismate mutase type II
628WSC domain
11MAC/Perforin domain
41950GPCR proteolysis site, GPS, motif
11Peptidase A4 family
88IPT/TIG domain
22MG2 domain
44FG-GAP repeat
314Transglutaminase-like superfamily
55ACT domain
22DIL domain
33HNH endonuclease
167FF domain
246NAC domain
336Proteasome/cyclosome repeat
8614START domain
314MOZ/SAS family
224Putative diphthamide synthesis protein
11Domain of unknown function UPF0086
11RibD C-terminal domain
527Domain found in IF2B/IF5
123Memo-like protein
112RNase P subunit p30
112Iron-sulfur cluster assembly protein
235RNA 2'-phosphotransferase, Tpt1 / KptA family
11Uncharacterised protein family UPF0047
112DNA primase small subunit
11Rpp14/Pop5 family
213Diphthamide synthase
22Ribosomal protein L37e
51015Nucleotidyltransferase domain
11Thiamine-binding protein
112eIF-6 family
9716Glycosyl hydrolase family 3 C-terminal domain
224Deoxyhypusine synthase
437Prefoldin subunit
11SRP19 protein
213Cobalamin adenosyltransferase
459Sulfite exporter TauE/SafE
36448050S ribosome-binding GTPase
11Mut7-C RNAse domain
11CYTH domain
112Ribosomal protein L14
11Protein of unknown function DUF84
33NYN domain
426Protein of unknown function DUF89
33TRAM domain
213Integral membrane protein DUF92
112Archease protein family (MTH1598/TM1083)
22Integral membrane protein EMC3/TMCO1-like
44TraB family
347DJ-1/PfpI family
325HD domain
11MoaC family
213tRNA intron endonuclease, catalytic C-terminal domain
639Amidohydrolase family
213tRNA-methyltransferase O
134Peptidyl-tRNA hydrolase PTH2
11Double-stranded DNA-binding domain
5510VIT family
112ATP synthase (F/14-kDa) subunit
123ATP synthase (E/31 kDa) subunit
156ATP synthase (C/AC39) subunit
22Translin family
336N2,N2-dimethylguanosine tRNA methyltransferase
71475REJ domain
55BNR/Asp-box repeat
22RyR domain
22Ribosome-binding factor A
112SCP-2 sterol transfer family
331245SAP domain
11Arsenical pump membrane protein
11CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
11Cytochrome c oxidase subunit VIa
516Glycosyl hydrolase family 30 TIM-barrel domain
11Glycosyl hydrolase family 59
11Aromatic-di-Alanine (AdAR) repeat
11Carboxypeptidase Taq (M32) metallopeptidase
134Synapsin, N-terminal domain
33TrkA-C domain
22D12 class N6 adenine-specific DNA methyltransferase
22Palmitoyl protein thioesterase
11Glycyl-tRNA synthetase beta subunit
11Gag P30 core shell protein
53860Kd inner membrane protein
11SURF1 family
11DAD family
11Hydroxyethylthiazole kinase family
112RHO protein GDP dissociation inhibitor
11Phosphatidylinositol transfer protein
11Phosphotriesterase family
145Aminopeptidase I zinc metalloprotease (M18)
123X-Pro dipeptidyl-peptidase (S15 family)
11Uncharacterized protein family UPF0054
33Nuclear transport factor 2 (NTF2) domain
11Adenosine-deaminase (editase) domain
62733Beige/BEACH domain
11Galactose binding lectin domain
121830DENN (AEX-3) domain
325MGS-like domain
112Repair protein Rad1/Rec1/Rad17
15520Sir2 family
4610Zn-finger in ubiquitin-hydrolases and other protein
11RNA polymerases M/15 Kd subunit
33UvrB/uvrC motif
123Dihydroneopterin aldolase
11Glycosyl hydrolase family 26
11Mannose-6-phosphate receptor
44Peptidase family M50
145Cytochrome C1 family
134PAZ domain
1212Piwi domain
2197199TRAF-type zinc finger
66AT hook motif
214263Formin Homology 2 Domain
33HAT (Half-A-TPR) repeat
11TFIIE beta subunit core domain
224ATP-dependent protease La (LON) substrate-binding domain
145PXA domain
11ParB-like nuclease domain
44Regulatory subunit of type II PKA R-subunit
112Sterile alpha motif (SAM)/Pointed domain
33SWIB/MDM2 domain
31821Vacuolar sorting protein 9 (VPS9) domain
99WH2 motif
5914Putative zinc finger in N-recognin (UBR box)
257Villin headpiece domain
11Laminin G domain
11Nitrile hydratase beta subunit
257Dynamin GTPase effector domain
426GYF domain
134BTB/POZ domain
224Methylenetetrahydrofolate reductase
11ML domain
11ATP-grasp domain
112Thymidylate kinase
10313PA domain
415Transcriptional Coactivator p15 (PC4)
123NAD(P) transhydrogenase beta subunit
268Proteasome activator pa28 beta subunit
11TrkA-N domain
44FAT domain
7714FATC domain
426Guanylate-binding protein, N-terminal domain
11Transcription initiation factor IIA, gamma subunit, helical domain
213Transcription initiation factor IID, 18kD subunit
11TFIIF, beta subunit HTH domain
11Ubiquinol-cytochrome C reductase complex 14kD subunit
11DHHA1 domain
55Linear amide C-N hydrolases, choloylglycine hydrolase family
112Transcription initiation factor IID, 31kD subunit
22Alpha adaptin AP2, C-terminal domain
11Cytochrome oxidase c subunit VIb
437HORMA domain