Peptidases • Trametes ljubarskyi CIRM-BRFM 1659 v1.0
Annotations/GenomesArtel1Pycci1Pycco1Pycco1662_1Pycsa1Tralj1Trave1TotalAnnotation Description
Merops
3773173673643763524332,586
63465449544962377Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
222221112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1411141211111588Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
953344432Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112127Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
112222111Water nucleophile; water bound by Gln and Glu; all endopeptidases
222222214Families of peptidase inhibitors not assigned to clans
1113
222222214
222222214Families of metallopeptidases not assigned to clans
17141618181722122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111217Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1135Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9111010118968Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
15171417141715109Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1012111111111278Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
556665740Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
24182222222322153Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
445555533Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22252726292534188Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1491171471441451421781,022Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
453444630Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333353424Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111116Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
223344321Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
10912131481379
11
11125