Yarrowia lipolytica YlCW001.
Image Credit: Cong Trinh
Image Credit: Cong Trinh
Yarrowia lipolytica YlCW001 is the most ionic liquid-tolerant oleaginous yeast published to date, tolerating up to 18% (v/v) 1-ethyl-3-methylimidazolium acetate ([EMIM][OAc]) (Walker et. al. 2019). YlCW001 was isolataed after 200 generations of adaptive laboratory evolution in [EMIM][OAc] from the parent strain, PO1F (ATCC MYA-2613). The ionic liquid-tolerant phenotype of YlCW001 is advantageous for novel biocatalysis in high concentrations of ionic liquids.
Reference:
Walker C, Ryu S, & Trinh CT (2019) Exceptional solvent
tolerance in Yarrowia lipolytica is enhanced by sterols.
Metabolic Engineering 54:83-95.
Genome Reference(s)
Please cite the following publication(s) if you use the data from this genome in your research:
Walker C, Ryu S, Haridas S, Na H, Zane M, LaButti K, Barry K, Grigoriev IV, Trinh CT
Draft Genome Assemblies of Ionic Liquid-Resistant Yarrowia lipolytica PO1f and Its Superior Evolved Strain, YlCW001.
Microbiol Resour Announc. 2020 Feb 27;9(9):. doi: 10.1128/MRA.01356-19
Walker C, Ryu S, Haridas S, Na H, Zane M, LaButti K, Barry K, Grigoriev IV, Trinh CT
Draft Genome Assemblies of Ionic Liquid-Resistant Yarrowia lipolytica PO1f and Its Superior Evolved Strain, YlCW001.
Microbiol Resour Announc. 2020 Feb 27;9(9):. doi: 10.1128/MRA.01356-19
